Abstract
The Pschorr reaction is a classical ring closure process for the formation of polycyclic systems in which two aryl moieties are joined together. It represents a bridge that connects diazonium ion chemistry with PAH synthesis. The Pschorr reaction has been employed as a key step in a number of carbocyclic and heterocyclic ring forming transformations for the synthesis of complex polycyclic molecules. Our continuing interest in diazonium ion chemistry and PAH chemistry prompted us to review the status of this transformation and to summarize the more recent developments in the use of this classical reaction.
Keywords: Pschorr reaction, intramolecular coupling, diazotization, dediazoniation, aryl radicals, isomerization by 1, 5-H migration, PAH and hetero-PAH synthesis
Current Organic Synthesis
Title: The Pschorr Reaction, a Fresh Look at a Classical Transformation
Volume: 6 Issue: 2
Author(s): Kenneth K. Laali and Mohammadreza Shokouhimehr
Affiliation:
Keywords: Pschorr reaction, intramolecular coupling, diazotization, dediazoniation, aryl radicals, isomerization by 1, 5-H migration, PAH and hetero-PAH synthesis
Abstract: The Pschorr reaction is a classical ring closure process for the formation of polycyclic systems in which two aryl moieties are joined together. It represents a bridge that connects diazonium ion chemistry with PAH synthesis. The Pschorr reaction has been employed as a key step in a number of carbocyclic and heterocyclic ring forming transformations for the synthesis of complex polycyclic molecules. Our continuing interest in diazonium ion chemistry and PAH chemistry prompted us to review the status of this transformation and to summarize the more recent developments in the use of this classical reaction.
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Cite this article as:
Laali K. Kenneth and Shokouhimehr Mohammadreza, The Pschorr Reaction, a Fresh Look at a Classical Transformation, Current Organic Synthesis 2009; 6 (2) . https://dx.doi.org/10.2174/157017909788167275
DOI https://dx.doi.org/10.2174/157017909788167275 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
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