Predicting the Pharmacological Targets of Astragalus membranaceus against Hypertensive Nephropathy

Zhou, B.; Carrillo-Larco, R.M.; Danaei, G.; Riley, L.M.; Paciorek, C.J.; Stevens, G.A. Gregg, E.W.; Bennett, J.E.; Solomon, B.; Singleton, R.K.; Sophiea, M.K.; Iurilli, M.L.C.; Lhoste, V.P.F.; Cowan, M.J.; Savin, S.; Woodward, M.; Balanova, Y.; Cifkova, R.; Damasceno, A.; Elliott, P.; Farzadfar, F.; He, J.; Ikeda, N.; Kengne, A.P.; Khang, Y-H.; Kim, H.C.; Laxmaiah, A.; Lin, H-H.; Margozzini Maira, P.; Miranda, J.J.; Neuhauser, H.; Sundström, J.; Varghese, C.; Widyahening, I.S.; Zdrojewski, T.; Abarca-Gómez, L.; Abdeen, Z.A.; Abdul Rahim, H.F.; Abu-Rmeileh, N.M.; Acosta-Cazares, B.; Adams, R.J.; Aekplakorn, W.; Afsana, K.; Afzal, S.; Agdeppa, I.A.; Aghazadeh-Attari, J.; Aguilar-Salinas, C.A.; Agyemang, C.; Ahmad, N.A.; Ahmadi, A.; Ahmadi, N.; Ahmadi, N.; Ahmadizar, F.; Ahmed, S.H.; Ahrens, W.; Ajlouni, K.; Al-Raddadi, R.; Alarouj, M.; AlBuhairan, F.; AlDhukair, S.; Ali, M.M.; Alkandari, A.; Alkerwi, A.; Allin, K.; Aly, E.; Amarapurkar, D.N.; Amougou, N.; Amouyel, P.; Andersen, L.B.; Anderssen, S.A.; Anjana, R.M.; Ansari-Moghaddam, A.; Ansong, D.; Aounallah-Skhiri, H.; Araújo, J.; Ariansen, I.; Aris, T.; Arku, R.E.; Arlappa, N.; Aryal, K.K.; Aspelund, T.; Assah, F.K.; Assunção, M.C.F.; Auvinen, J.; Avdićová, M.; Azevedo, A.; Azimi-Nezhad, M.; Azizi, F.; Azmin, M.; Babu, B.V.; Bahijri, S.; Balakrishna, N.; Bamoshmoosh, M.; Banach, M.; Banadinović, M.; Bandosz, P.; Banegas, J.R.; Baran, J.; Barbagallo, C.M.; Barceló, A.; Barkat, A.; Barreto, M.; Barros, A.J.D.; Barros, M.V.G.; Bartosiewicz, A.; Basit, A.; Bastos, J.L.D.; Bata, I.; Batieha, A.M.; Batyrbek, A.; Baur, L.A.; Beaglehole, R.; Belavendra, A.; Ben Romdhane, H.; Benet, M.; Benson, L.S.; Berkinbayev, S.; Bernabe-Ortiz, A.; Bernotiene, G.; Bettiol, H.; Bezerra, J.; Bhagyalaxmi, A.; Bhargava, S.K.; Bia, D.; Biasch, K.; Bika Lele, E.C.; Bikbov, M.M.; Bista, B.; Bjerregaard, P.; Bjertness, E.; Bjertness, M.B.; Björkelund, C.; Bloch, K.V.; Blokstra, A.; Bo, S.; Bobak, M.; Boeing, H.; Boggia, J.G.; Boissonnet, C.P.; Bojesen, S.E.; Bongard, V.; Bonilla-Vargas, A.; Bopp, M.; Borghs, H.; Bovet, P.; Boyer, C.B.; Braeckman, L.; Brajkovich, I.; Branca, F.; Breckenkamp, J.; Brenner, H.; Brewster, L.M.; Briceño, Y.; Brito, M.; Bruno, G.; Bueno-de-Mesquita, H.B.; Bueno, G.; Bugge, A.; Burns, C.; Bursztyn, M.; Cabrera de León, A.; Cacciottolo, J.; Cameron, C.; Can, G.; Cândido, A.P.C.; Capanzana, M.V.; Čapková, N.; Capuano, E.; Capuano, V.; Cardoso, V.C.; Carlsson, A.C.; Carvalho, J.; Casanueva, F.F.; Censi, L.; Cervantes-Loaiza, M.; Chadjigeorgiou, C.A.; Chamukuttan, S.; Chan, A.W.; Chan, Q.; Chaturvedi, H.K.; Chaturvedi, N.; Chee, M.L.; Chen, C-J.; Chen, F.; Chen, H.; Chen, S.; Chen, Z.; Cheng, C-Y.; Cheraghian, B.; Cherkaoui Dekkaki, I.; Chetrit, A.; Chien, K-L.; Chiolero, A.; Chiou, S-T.; Chirita-Emandi, A.; Chirlaque, M-D.; Cho, B.; Christensen, K.; Christofaro, D.G.; Chudek, J.; Cinteza, E.; Claessens, F.; Clarke, J.; Clays, E.; Cohen, E.; Concin, H.; Cooper, C.; Coppinger, T.C.; Costanzo, S.; Cottel, D.; Cowell, C.; Craig, C.L.; Crampin, A.C.; Crujeiras, A.B.; Cruz, J.J.; Csilla, S.; Cui, L.; Cureau, F.V.; Cuschieri, S.; D’Arrigo, G.; d’Orsi, E.; Dallongeville, J.; Dankner, R.; Dantoft, T.M.; Dauchet, L.; Davletov, K.; De Backer, G.; De Bacquer, D.; De Curtis, A.; de Gaetano, G.; De Henauw, S.; de Oliveira, P.D.; De Ridder, D.; De Smedt, D.; Deepa, M.; Deev, A.D.; DeGennaro, V.J.; Delisle, H.; Demarest, S.; Dennison, E.; Deschamps, V.; Dhimal, M.; Di Castelnuovo, A.F.; Dias-da-Costa, J.S.; Diaz, A.; Dickerson, T.T.; Dika, Z.; Djalalinia, S.; Do, H.T.P.; Dobson, A.J.; Donfrancesco, C.; Donoso, S.P.; Döring, A.; Dorobantu, M.; Dörr, M.; Doua, K.; Dragano, N.; Drygas, W.; Duante, C.A.; Duboz, P.; Duda, R.B.; Dulskiene, V.; Dushpanova, A.; Džakula, A.; Dzerve, V.; Dziankowska-Zaborszczyk, E.; Eddie, R.; Eftekhar, E.; Eggertsen, R.; Eghtesad, S.; Eiben, G.; Ekelund, U.; El-Khateeb, M.; El Ati, J.; Eldemire-Shearer, D.; Eliasen, M.; Elosua, R.; Erasmus, R.T.; Erbel, R.; Erem, C.; Eriksen, L.; Eriksson, J.G.; Escobedo-de la Peña, J.; Eslami, S.; Esmaeili, A.; Evans, A.; Faeh, D.; Fakhretdinova, A.A.; Fall, C.H.; Faramarzi, E.; Farjam, M.; Fattahi, M.R.; Fawwad, A.; Felix-Redondo, F.J.; Felix, S.B.; Ferguson, T.S.; Fernandes, R.A.; Fernández-Bergés, D.; Ferrante, D.; Ferrao, T.; Ferrari, M.; Ferrario, M.M.; Ferreccio, C.; Ferreira, H.S.; Ferrer, E.; Ferrieres, J.; Figueiró, T.H.; Fink, G.; Fischer, K.; Foo, L.H.; Forsner, M.; Fouad, H.M.; Francis, D.K.; Franco, M.C.; Frikke-Schmidt, R.; Frontera, G.; Fuchs, F.D.; Fuchs, S.C.; Fujita, Y.; Fumihiko, M.; Furdela, V.; Furer, A.; Furusawa, T.; Gaciong, Z.; Galbarczyk, A.; Galenkamp, H.; Galvano, F.; Gao, J.; Gao, P.; Garcia-de-la-Hera, M.; Garcia, P.; Gareta, D.; Garnett, S.P.; Gaspoz, J-M.; Gasull, M.; Gazzinelli, A.; Gehring, U.; Geleijnse, J.M.; George, R.; Ghanbari, A.; Ghasemi, E.; Gheorghe-Fronea, OF.; Ghimire, A.; Gialluisi, A.; Giampaoli, S.; Gieger, C.; Gill, T.K.; Giovannelli, J.; Gironella, G.; Giwercman, A.; Gkiouras, K.; Goldberg, M.; Goldsmith, R.A.; Gomez, L.F.; Gomula, A.; Gonçalves, H.; Gonçalves, M.; Gonçalves Cordeiro da Silva, B.; Gonzalez-Chica, D.A.; Gonzalez-Gross, M.; González-Rivas, J.P.; González-Villalpando, C.; González-Villalpando, M-E.; Gonzalez, A.R.; Gorbea, M.B.; Gottrand, F.; Graff-Iversen, S.; Grafnetter, D.; Grajda, A.; Grammatikopoulou, M.G.; Gregor, R.D.; Grodzicki, T.; Grosso, G.; Gruden, G.; Gu, D.; Guan, O.P.; Gudmundsson, E.F.; Gudnason, V.; Guerrero, R.; Guessous, I.; Guimaraes, A.L.; Gulliford, M.C.; Gunnlaugsdottir, J.; Gunter, M.J.; Gupta, P.C.; Gupta, R.; Gureje, O.; Gurzkowska, B.; Gutierrez, L.; Gutzwiller, F.; Ha, S.; Hadaegh, F.; Haghshenas, R.; Hakimi, H.; Halkjær, J.; Hambleton, I.R.; Hamzeh, B.; Hange, D.; Hanif, A.A.M.; Hantunen, S.; Hao, J.; Hardman, C.M.; Hari Kumar, R.; Hashemi-Shahri, S.M.; Hata, J.; Haugsgjerd, T.; Hayes, A.J.; He, Y.; Heier, M.; Hendriks, M.E.; Henrique, R.S.; Henriques, A.; Hernandez Cadena, L.; Herqutanto, ; Herrala, S.; Heshmat, R.; Hill, A.G.; Ho, S.Y.; Ho, S.C.; Hobbs, M.; Holdsworth, M.; Homayounfar, R.; Horasan Dinc, G.; Horimoto, A.R.V.R.; Hormiga, C.M.; Horta, B.L.; Houti, L.; Howitt, C.; Htay, T.T.; Htet, A.S.; Htike, M.M.T.; Hu, Y.; Huerta, J.M.; Huhtaniemi, I.T.; Huiart, L.; Huisman, M.; Husseini, A.S.; Huybrechts, I.; Hwalla, N.; Iacoviello, L.; Iannone, A.G.; Ibrahim, M.M.; Ibrahim Wong, N.; Ikram, M.A.; Iotova, V.; Irazola, V.E.; Ishida, T.; Isiguzo, G.C.; Islam, M.; Islam, S.M.S.; Iwasaki, M.; Jackson, R.T.; Jacobs, J.M.; Jaddou, H.Y.; Jafar, T.; James, K.; Jamrozik, K.; Janszky, I.; Janus, E.; Jarvelin, M-R.; Jasienska, G.; Jelaković, A.; Jelaković, B.; Jennings, G.; Jha, A.K.; Jiang, C.Q.; Jimenez, R.O.; Jöckel, K-H.; Joffres, M.; Johansson, M.; Jokelainen, J.J.; Jonas, J.B.; Jørgensen, T.; Joshi, P.; Joukar, F.; Jóżwiak, J.; Juolevi, A.; Jurak, G.; Jureša, V.; Kaaks, R.; Kafatos, A.; Kajantie, E.O.; Kalmatayeva, Z.; Kalpourtzi, N.; Kalter-Leibovici, O.; Kampmann, F.B.; Kannan, S.; Karaglani, E.; Kårhus, L.L.; Karki, K.B.; Katibeh, M.; Katz, J.; Kauhanen, J.; Kaur, P.; Kavousi, M.; Kazakbaeva, G.M.; Keil, U.; Keinan Boker, L.; Keinänen-Kiukaanniemi, S.; Kelishadi, R.; Kemper, H.C.G.; Keramati, M.; Kerimkulova, A.; Kersting, M.; Key, T.; Khader, Y.S.; Khalili, D.; Khaw, K-T.; Kheiri, B.; Kheradmand, M.; Khosravi, A.; Kiechl-Kohlendorfer, U.; Kiechl, S.; Killewo, J.; Kim, D.W.; Kim, J.; Klakk, H.; Klimek, M.; Klumbiene, J.; Knoflach, M.; Kolle, E.; Kolsteren, P.; Kontto, J.P.; Korpelainen, R.; Korrovits, P.; Kos, J.; Koskinen, S.; Kouda, K.; Kowlessur, S.; Koziel, S.; Kratenova, J.; Kriaucioniene, V.; Kristensen, P.L.; Krokstad, S.; Kromhout, D.; Kruger, H.S.; Kubinova, R.; Kuciene, R.; Kujala, U.M.; Kulaga, Z.; Kumar, R.K.; Kurjata, P.; Kusuma, Y.S.; Kutsenko, V.; Kuulasmaa, K.; Kyobutungi, C.; Laatikainen, T.; Lachat, C.; Laid, Y.; Lam, T.H.; Landrove, O.; Lanska, V.; Lappas, G.; Larijani, B.; Latt, T.S.; Le Coroller, G.; Le Nguyen Bao, K.; Le, T.D.; Lee, J.; Lee, J.; Lehmann, N.; Lehtimäki, T.; Lemogoum, D.; Levitt, N.S.; Li, Y.; Lilly, C.L.; Lim, W-Y.; Lima-Costa, M.F.; Lin, X.; Lin, Y-T.; Lind, L.; Lingam, V.; Linneberg, A.; Lissner, L.; Litwin, M.; Lo, W-C.; Loit, H-M.; Lopez-Garcia, E.; Lopez, T.; Lotufo, P.A.; Lozano, J.E.; Lukačević Lovrenčić, I.; Lukrafka, J.L.; Luksiene, D.; Lundqvist, A.; Lundqvist, R.; Lunet, N.; Lustigová, M.; Luszczki, E.; Ma, G.; Ma, J.; Machado-Coelho, G.L.L.; Machado-Rodrigues, A.M.; Macia, E.; Macieira, L.M.; Madar, A.A.; Maggi, S.; Magliano, D.J.; Magriplis, E.; Mahasampath, G.; Maire, B.; Majer, M.; Makdisse, M.; Malekzadeh, F.; Malekzadeh, R.; Malhotra, R.; Mallikharjuna Rao, K.; Malyutina, S.K.; Maniego, L.V.; Manios, Y.; Mann, J.I.; Mansour-Ghanaei, F.; Manzato, E.; Marcil, A.; Mårild, S.B.; Marinović Glavić, M.; Marques-Vidal, P.; Marques, L.P.; Marrugat, J.; Martorell, R.; Mascarenhas, L.P.; Matasin, M.; Mathiesen, E.B.; Mathur, P.; Matijasevich, A.; Matlosz, P.; Matsha, T.E.; Mavrogianni, C.; Mbanya, J.C.N.; Mc Donald Posso, A.J.; McFarlane, S.R.; McGarvey, S.T.; McLachlan, S.; McLean, R.M.; McLean, S.B.; McNulty, B.A.; Mediene Benchekor, S.; Medzioniene, J.; Mehdipour, P.; Mehlig, K.; Mehrparvar, A.H.; Meirhaeghe, A.; Meisinger, C.; Mendoza Montano, C.; Menezes, A.M.B.; Menon, G.R.; Mereke, A.; Meshram, I.I.; Metspalu, A.; Meyer, H.E.; Mi, J.; Michels, N.; Mikkel, K.; Milkowska, K.; Miller, J.C.; Minderico, C.S.; Mini, G.K.; Mirjalili, M.R.; Mirrakhimov, E.; Mišigoj-Duraković, M.; Modesti, P.A.; Moghaddam, S.S.; Mohajer, B.; Mohamed, M.K.; Mohamed, S.F.; Mohammad, K.; Mohammadi, M.R.; Mohammadi, Z.; Mohammadifard, N.; Mohammadpourhodki, R.; Mohan, V.; Mohanna, S.; Mohd Yusoff, M.F.; Mohebbi, I.; Mohebi, F.; Moitry, M.; Møllehave, L.T.; Molnár, D.; Momenan, A.; Mondo, C.K.; Monterrubio-Flores, E.; Monyeki, K.D.K.; Moon, J.S.; Moosazadeh, M.; Moreira, L.B.; Morejon, A.; Moreno, L.A.; Morgan, K.; Moschonis, G.; Mossakowska, M.; Mostafa, A.; Mostafavi, S-A.; Mota, J.; Motlagh, M.E.; Motta, J.; Moura-dos-Santos, M.A.; Mridha, M.K.; Msyamboza, K.P.; Mu, T.T.; Muhihi, A.J.; Muiesan, M.L.; Müller-Nurasyid, M.; Murphy, N.; Mursu, J.; Musa, K.I.; Musić Milanović, S.; Musil, V.; Mustafa, N.; Nabipour, I.; Naderimagham, S.; Nagel, G.; Naidu, B.M.; Najafi, F.; Nakamura, H.; Námešná, J.; Nang, E.E.K.; Nangia, V.B.; Narake, S.; Ndiaye, N.C.; Neal, W.A.; Nejatizadeh, A.; Nenko, I.; Neovius, M.; Nguyen, C.T.; Nguyen, N.D.; Nguyen, Q.V.; Nguyen, Q.N.; Nieto-Martínez, R.E.; Niiranen, T.J.; Nikitin, Y.P.; Ninomiya, T.; Nishtar, S.; Njelekela, M.A.; Noale, M.; Noboa, O.A.; Noorbala, A.A.; Norat, T.; Nordendahl, M.; Nordestgaard, B.G.; Noto, D.; Nowak-Szczepanska, N.; Nsour, M.A.; Nunes, B.; O’Neill, T.W.; O’Reilly, D.; Ochimana, C.; Oda, E.; Odili, A.N.; Oh, K.; Ohara, K.; Ohtsuka, R.; Olié, V.; Olinto, M.T.A.; Oliveira, I.O.; Omar, M.A.; Onat, A.; Ong, S.K.; Ono, L.M.; Ordunez, P.; Ornelas, R.; Ortiz, P.J.; Osmond, C.; Ostojic, S.M.; Ostovar, A.; Otero, J.A.; Overvad, K.; Owusu-Dabo, E.; Paccaud, F.M.; Padez, C.; Pahomova, E.; Paiva, K.M.; Pająk, A.; Palli, D.; Palmieri, L.; Pan, W-H.; Panda-Jonas, S.; Panza, F.; Paoli, M.; Papandreou, D.; Park, S-W.; Park, S.; Parnell, W.R.; Parsaeian, M.; Pasquet, P.; Patel, N.D.; Pavlyshyn, H.; Pećin, I.; Pednekar, M.S.; Pedro, J.M.; Peer, N.; Peixoto, S.V.; Peltonen, M.; Pereira, A.C.; Peres, K.G.D.A.; Peres, M.A.; Peters, A.; Petkeviciene, J.; Peykari, N.; Pham, S.T.; Pichardo, R.N.; Pigeot, I.; Pikhart, H.; Pilav, A.; Pilotto, L.; Pitakaka, F.; Piwonska, A.; Pizarro, A.; Plans-Rubió, P.; Polašek, O.; Porta, M.; Poudyal, A.; Pourfarzi, F.; Pourshams, A.; Poustchi, H.; Pradeepa, R.; Price, A.J.; Price, J.F.; Providencia, R.; Puhakka, S.E.; Puiu, M.; Punab, M.; Qasrawi, R.F.; Qorbani, M.; Queiroz, D.; Quoc Bao, T.; Radić, I.; Radisauskas, R.; Rahimikazerooni, S.; Rahman, M.; Raitakari, O.; Raj, M.; Rakhimova, E.M.; Ramachandra Rao, S.; Ramachandran, A.; Ramos, E.; Rampal, L.; Rampal, S.; Rangel Reina, D.A.; Rarra, V.; Rech, C.R.; Redon, J.; Reganit, P.F.M.; Regecová, V.; Revilla, L.; Rezaianzadeh, A.; Ribeiro, R.; Riboli, E.; Richter, A.; Rigo, F.; Rinke de Wit, T.F.; Ritti-Dias, R.M.; Robitaille, C.; Rodríguez-Artalejo, F.; Rodriguez-Perez, M.C.; Rodríguez-Villamizar, L.A.; Roggenbuck, U.; Rojas-Martinez, R.; Romaguera, D.; Romeo, E.L.; Rosengren, A.; Roy, J.G.R.; Rubinstein, A.; Ruidavets, J-B.; Ruiz-Betancourt, B.S.; Ruiz-Castell, M.; Rusakova, I.A.; Russo, P.; Rutkowski, M.; Sabanayagam, C.; Sabbaghi, H.; Sachdev, H.S.; Sadjadi, A.; Safarpour, A.R.; Safi, S.; Safiri, S.; Saidi, O.; Sakarya, S.; Saki, N.; Salanave, B.; Salazar Martinez, E.; Salmerón, D.; Salomaa, V.; Salonen, J.T.; Salvetti, M.; Sánchez-Abanto, J.; Sans, S.; Santos, D.A.; Santos, I.S.; Santos, L.C.; Santos, M.P.; Santos, R.; Saramies, J.L.; Sardinha, L.B.; Sarganas, G.; Sarrafzadegan, N.; Sathish, T.; Saum, K-U.; Savva, S.; Sawada, N.; Sbaraini, M.; Scazufca, M.; Schaan, B.D.; Schargrodsky, H.; Schipf, S.; Schmidt, C.O.; Schnohr, P.; Schöttker, B.; Schramm, S.; Schultsz, C.; Schutte, A.E.; Sebert, S.; Sein, A.A.; Sen, A.; Senbanjo, I.O.; Sepanlou, S.G.; Servais, J.; Shalnova, S.A.; Shamah-Levy, T.; Shamshirgaran, M.; Shanthirani, C.S.; Sharafkhah, M.; Sharma, S.K.; Shaw, J.E.; Shayanrad, A.; Shayesteh, A.A.; Shi, Z.; Shibuya, K.; Shimizu-Furusawa, H.; Shin, D.W.; Shirani, M.; Shiri, R.; Shrestha, N.; Si-Ramlee, K.; Siani, A.; Siantar, R.; Sibai, A.M.; Silva, C.R.M.; Silva, D.A.S.; Simon, M.; Simons, J.; Simons, L.A.; Sjöström, M.; Slowikowska-Hilczer, J.; Slusarczyk, P.; Smeeth, L.; So, H-K.; Soares, F.C.; Sobngwi, E.; Söderberg, S.; Soemantri, A.; Sofat, R.; Solfrizzi, V.; Somi, M.H.; Sonestedt, E.; Song, Y.; Sørensen, T.I.A.; Sørgjerd, E.P.; Sorić, M.; Sossa Jérome, C.; Soumaré, A.; Sparboe-Nilsen, B.; Sparrenberger, K.; Staessen, J.A.; Starc, G.; Stavreski, B.; Steene-Johannessen, J.; Stehle, P.; Stein, A.D.; Stergiou, G.S.; Stessman, J.; Stieber, J.; Stöckl, D.; Stocks, T.; Stokwiszewski, J.; Stronks, K.; Strufaldi, M.W.; Suka, M.; Sun, C-A.; Sung, Y-T.; Suriyawongpaisal, P.; Sy, R.G.; Syddall, H.E.; Sylva, R.C.; Szklo, M.; Tai, E.S.; Tammesoo, M-L.; Tamosiunas, A.; Tan, E.J.; Tang, X.; Tanser, F.; Tao, Y.; Tarawneh, M.R.; Tarqui-Mamani, C.B.; Taylor, A.; Taylor, J.; Tebar, W.R.; Tell, G.S.; Tello, T.; Tham, Y.C.; Thankappan, K.R.; Theobald, H.; Theodoridis, X.; Thijs, L.; Thinggaard, M.; Thomas, N.; Thorand, B.; Thuesen, B.H.; Timmermans, E.J.; Tjandrarini, D.H.; Tjonneland, A.; Toft, U.; Tolonen, H.K.; Tolstrup, J.S.; Topbas, M.; Topór-Madry, R.; Tormo, M.J.; Tornaritis, M.J.; Torrent, M.; Torres-Collado, L.; Touloumi, G.; Traissac, P.; Triantafyllou, A.; Trichopoulos, D.; Trichopoulou, A.; Trinh, O.T.H.; Trivedi, A.; Tshepo, L.; Tsugane, S.; Tuliakova, A.M.; Tulloch-Reid, M.K.; Tullu, F.; Tuomainen, T-P.; Tuomilehto, J.; Turley, M.L.; Twig, G.; Tynelius, P.; Tzourio, C.; Ueda, P.; Ugel, E.; Ulmer, H.; Uusitalo, H.M.T.; Valdivia, G.; Valvi, D.; van Dam, R.M.; van den Born, B-J.; Van der Heyden, J.; van der Schouw, Y.T.; Van Herck, K.; Van Minh, H.; Van Schoor, N.M.; van Valkengoed, I.G.M.; van Zutphen, E.M.; Vanderschueren, D.; Vanuzzo, D.; Varbo, A.; Vasan, S.K.; Vega, T.; Veidebaum, T.; Velasquez-Melendez, G.; Veronesi, G.; Verschuren, W.M.M.; Verstraeten, R.; Victora, C.G.; Viet, L.; Villalpando, S.; Vineis, P.; Vioque, J.; Virtanen, J.K.; Visvikis-Siest, S.; Viswanathan, B.; Vlasoff, T.; Vollenweider, P.; Voutilainen, A.; Wade, A.N.; Walton, J.; Wambiya, E.O.A.; Wan Bebakar, W.M.; Wan Mohamud, W.N.; Wanderley Júnior, R.S.; Wang, M-D.; Wang, N.; Wang, Q.; Wang, X.; Wang, Y.X.; Wang, Y-W.; Wannamethee, S.G.; Wareham, N.; Wei, W.; Weres, A.; Werner, B.; Whincup, P.H.; Widhalm, K.; Wiecek, A.; Wilks, R.J.; Willeit, J.; Willeit, P.; Williams, E.A.; Wilsgaard, T.; Wojtyniak, B.; Wong-McClure, R.A.; Wong, A.; Wong, T.Y.; Woo, J.; Wu, F.C.; Wu, S.; Wyszynska, J.; Xu, H.; Xu, L.; Yaacob, N.A.; Yan, W.; Yang, L.; Yang, X.; Yang, Y.; Yasuharu, T.; Ye, X.; Yiallouros, P.K.; Yoosefi, M.; Yoshihara, A.; You, S-L.; Younger-Coleman, N.O.; Yusoff, A.F.; Zainuddin, A.A.; Zakavi, S.R.; Zamani, F.; Zambon, S.; Zampelas, A.; Zapata, M.E.; Zaw, K.K.; Zejglicova, K.; Zeljkovic Vrkic, T.; Zeng, Y.; Zhang, L.; Zhang, Z-Y.; Zhao, D.; Zhao, M-H.; Zhen, S.; Zheng, Y.; Zholdin, B.; Zhu, D.; Zins, M.; Zitt, E.; Zocalo, Y.; Zoghlami, N.; Zuñiga Cisneros, J.; Ezzati, M. Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: A pooled analysis of 1201 population-representative studies with 104 million participants. Lancet, 2021, 398(10304), 957-980.
[http://dx.doi.org/10.1016/S0140-6736(21)01330-1] [PMID: 34450083]

Wu, P.; Green, M.; Myers, J.E. Hypertensive disorders of pregnancy. BMJ, 2023, 381, e071653.
[http://dx.doi.org/10.1136/bmj-2022-071653] [PMID: 37391211]

Whelton, P.K.; Carey, R.M.; Mancia, G.; Kreutz, R.; Bundy, J.D.; Williams, B. Harmonization of the American College of Cardiology/American Heart Association and European Society of Cardiology/European Society of Hypertension Blood pressure/Hypertension guidelines: Comparisons, reflections, and recommendations. Circulation, 2022, 146(11), 868-877.
[http://dx.doi.org/10.1161/CIRCULATIONAHA.121.054602] [PMID: 35950927]

Ungvari, Z.; Toth, P.; Tarantini, S.; Prodan, C.I.; Sorond, F.; Merkely, B.; Csiszar, A. Hypertension-induced cognitive impairment: From pathophysiology to public health. Nat. Rev. Nephrol., 2021, 17(10), 639-654.
[http://dx.doi.org/10.1038/s41581-021-00430-6] [PMID: 34127835]

Khoury, M.; Urbina, E.M. Hypertension in adolescents: Diagnosis, treatment, and implications. Lancet Child Adolesc. Health, 2021, 5(5), 357-366.
[http://dx.doi.org/10.1016/S2352-4642(20)30344-8] [PMID: 33711291]

He, F.J.; Tan, M.; Ma, Y.; MacGregor, G.A. Salt reduction to prevent hypertension and cardiovascular disease. J. Am. Coll. Cardiol., 2020, 75(6), 632-647.
[http://dx.doi.org/10.1016/j.jacc.2019.11.055] [PMID: 32057379]

Burnier, M.; Damianaki, A. Hypertension as cardiovascular risk factor in chronic kidney disease. Circ. Res., 2023, 132(8), 1050-1063.
[http://dx.doi.org/10.1161/CIRCRESAHA.122.321762] [PMID: 37053276]

Sequeira-Lopez, M.L.S.; Gomez, R.A. Renin cells, the kidney, and hypertension. Circ. Res., 2021, 128(7), 887-907.
[http://dx.doi.org/10.1161/CIRCRESAHA.121.318064] [PMID: 33793334]

Freedman, B.I.; Cohen, A.H. Hypertension-attributed nephropathy: What’s in a name? Nat. Rev. Nephrol., 2016, 12(1), 27-36.
[http://dx.doi.org/10.1038/nrneph.2015.172] [PMID: 26553514]

Udani, S.; Lazich, I.; Bakris, G.L. Epidemiology of hypertensive kidney disease. Nat. Rev. Nephrol., 2011, 7(1), 11-21.
[http://dx.doi.org/10.1038/nrneph.2010.154] [PMID: 21079654]

Lucero, C.M.; Prieto-Villalobos, J.; Marambio-Ruiz, L.; Balmazabal, J.; Alvear, T.F.; Vega, M.; Barra, P.; Retamal, M.A.; Orellana, J.A.; Gómez, G.I. Hypertensive nephropathy: Unveiling the possible involvement of hemichannels and pannexons. Int. J. Mol. Sci., 2022, 23(24), 15936.
[http://dx.doi.org/10.3390/ijms232415936] [PMID: 36555574]

Stompór, T.; Perkowska-Ptasińska, A. Hypertensive kidney disease: True epidemic or rare disease? Pol. Arch. Intern. Med., 2020, 130(2), 130-139.
[http://dx.doi.org/10.20452/pamw.15150] [PMID: 31964856]

Koopman, J.J.E.; van Essen, M.F.; Rennke, H.G.; de Vries, A.P.J.; van Kooten, C. Deposition of the membrane attack complex in healthy and diseased human kidneys. Front. Immunol., 2021, 11, 599974.
[http://dx.doi.org/10.3389/fimmu.2020.599974] [PMID: 33643288]

Fay, K.S.; Cohen, D.L. Resistant hypertension in people with CKD: A review. Am. J. Kidney Dis., 2021, 77(1), 110-121.
[http://dx.doi.org/10.1053/j.ajkd.2020.04.017] [PMID: 32712185]

Yang, C.; Gao, B.; Zhao, X.; Su, Z.; Sun, X.; Wang, H.Y.; Zhang, P.; Wang, R.; Liu, J.; Tang, W.; Zhang, D.; Chu, H.; Wang, J.; Wang, F.; Wang, S.; Zuo, L.; Wang, Y.; Yu, F.; Wang, H.; Zhang, L.; Zhang, H.; Yang, L.; Chen, J.; Zhao, M.H. Executive summary for China kidney disease network (CK-NET) 2016 Annual Data Report. Kidney Int., 2020, 98(6), 1419-1423.
[http://dx.doi.org/10.1016/j.kint.2020.09.003] [PMID: 33276868]

Jia, Q.; Wang, L.; Zhang, X.; Ding, Y.; Li, H.; Yang, Y.; Zhang, A.; Li, Y.; Lv, S.; Zhang, J. Prevention and treatment of chronic heart failure through Traditional Chinese Medicine: Role of the gut microbiota. Pharmacol. Res., 2020, 151, 104552.
[http://dx.doi.org/10.1016/j.phrs.2019.104552] [PMID: 31747557]

Hu, Y.W. Chinese herbal medicine use and risk of end-stage renal disease in patients with chronic kidney disease: Is there an immortal time bias? Kidney Int., 2016, 90(1), 227-228.
[http://dx.doi.org/10.1016/j.kint.2016.03.044] [PMID: 27312455]

Zhang, H.W.; Lin, Z.X.; Xu, C.; Leung, C.; Chan, L.S. Astragalus (A Traditional Chinese Medicine) for treating chronic kidney disease. Cochrane Libr., 2014, 2014(10), CD008369.
[http://dx.doi.org/10.1002/14651858.CD008369.pub2] [PMID: 25335553]

Zhong, Y.; Deng, Y.; Chen, Y.; Chuang, P.Y.; Cijiang, He J. Therapeutic use of traditional Chinese herbal medications for chronic kidney diseases. Kidney Int., 2013, 84(6), 1108-1118.
[http://dx.doi.org/10.1038/ki.2013.276] [PMID: 23868014]

Cui, X.; Trinh, K.; Wang, Y.J. Chinese herbal medicine for chronic neck pain due to cervical degenerative disc disease. Cochrane Libr., 2010, 2010(1), CD006556.
[http://dx.doi.org/10.1002/14651858.CD006556.pub2] [PMID: 20091597]

Chen, Z.; Liu, L.; Gao, C.; Chen, W.; Vong, C.T.; Yao, P.; Yang, Y.; Li, X.; Tang, X.; Wang, S.; Wang, Y. Astragali Radix (Huangqi): A promising edible immunomodulatory herbal medicine. J. Ethnopharmacol., 2020, 258, 112895.
[http://dx.doi.org/10.1016/j.jep.2020.112895] [PMID: 32330511]

Zhang, W.; Cui, Y.; Zhang, J. Multi metabolomics-based analysis of application of Astragalus membranaceus in the treatment of hyperuricemia. Front. Pharmacol., 2022, 13, 948939.
[http://dx.doi.org/10.3389/fphar.2022.948939] [PMID: 35935868]

Xue, B.; Li, J.; Chai, Q.; Liu, Z.; Chen, L. Effect of total flavonoid fraction of Astragalus complanatus R. Brown on angiotensin II-induced portal-vein contraction in hypertensive rats. Phytomedicine, 2008, 15(9), 759-762.
[http://dx.doi.org/10.1016/j.phymed.2007.11.030] [PMID: 18406589]

Li, N.Y.; Li, X.L.; Zhai, X.P.; Wang, Q.Y.; Zhang, X.W.; Zhao, F.; Wang, X.F.; Fan, J.Y.; Bai, F.; Yu, J. Effects of Mongolia Astragali Radix in protecting early cardiac and nephritic functions of patients of hypertension with metabolic syndrome. Zhongguo Zhong Yao Za Zhi, 2016, 41(21), 4051-4059.
[PMID: 28929695]

Hou, G.; Jiang, Y.; Zheng, Y. Mechanism of Radix Astragali and Radix SalviaeMiltiorrhizae ameliorates hypertensive renal damage. BioMed Res. Int., 2021, 2021, 5598351.
[http://dx.doi.org/10.1155/2021/5598351]

Hopkins, A.L. Network pharmacology. Nat. Biotechnol., 2007, 25(10), 1110-1111.
[http://dx.doi.org/10.1038/nbt1007-1110] [PMID: 17921993]

Zhang, R.; Zhu, X.; Bai, H.; Ning, K. Network pharmacology databases for Traditional Chinese Medicine: Review and assessment. Front. Pharmacol., 2019, 10, 123.
[http://dx.doi.org/10.3389/fphar.2019.00123] [PMID: 30846939]

Nogales, C.; Mamdouh, Z.M.; List, M.; Kiel, C.; Casas, A.I.; Schmidt, H.H.H.W. Network pharmacology: Curing causal mechanisms instead of treating symptoms. Trends Pharmacol. Sci., 2022, 43(2), 136-150.
[http://dx.doi.org/10.1016/j.tips.2021.11.004] [PMID: 34895945]

Zhao, L.; Zhang, H.; Li, N.; Chen, J.; Xu, H.; Wang, Y.; Liang, Q. Network pharmacology, a promising approach to reveal the pharmacology mechanism of Chinese medicine formula. J. Ethnopharmacol., 2023, 309, 116306.
[http://dx.doi.org/10.1016/j.jep.2023.116306] [PMID: 36858276]

Yuan, Z.; Pan, Y.; Leng, T.; Chu, Y.; Zhang, H.; Ma, J.; Ma, X. Progress and prospects of research ideas and methods in the network pharmacology of Traditional Chinese Medicine. J. Pharm. Pharm. Sci., 2022, 25, 218-226.
[http://dx.doi.org/10.18433/jpps32911] [PMID: 35760072]

Li, X.; Wei, S.; Niu, S.; Ma, X.; Li, H.; Jing, M.; Zhao, Y. Network pharmacology prediction and molecular docking-based strategy to explore the potential mechanism of Huanglian Jiedu Decoction against sepsis. Comput. Biol. Med., 2022, 144, 105389.
[http://dx.doi.org/10.1016/j.compbiomed.2022.105389] [PMID: 35303581]

Jiashuo, W.U.; Fangqing, Z.; Zhuangzhuang, L.I.; Weiyi, J.; Yue, S. Integration strategy of network pharmacology in Traditional Chinese Medicine: A narrative review. J. Tradit. Chin. Med., 2022, 42(3), 479-486.
[PMID: 35610020]

Ru, J.; Li, P.; Wang, J.; Zhou, W.; Li, B.; Huang, C.; Li, P.; Guo, Z.; Tao, W.; Yang, Y.; Xu, X.; Li, Y.; Wang, Y.; Yang, L. TCMSP: A database of systems pharmacology for drug discovery from herbal medicines. J. Cheminform., 2014, 6(1), 13.
[http://dx.doi.org/10.1186/1758-2946-6-13] [PMID: 24735618]

Xu, X.; Zhang, W.; Huang, C.; Li, Y.; Yu, H.; Wang, Y.; Duan, J.; Ling, Y. A novel chemometric method for the prediction of human oral bioavailability. Int. J. Mol. Sci., 2012, 13(6), 6964-6982.
[http://dx.doi.org/10.3390/ijms13066964] [PMID: 22837674]

Stelzer, G.; Rosen, N.; Plaschkes, I. The genecards suite: From gene data mining to disease genome sequence analyses. Curr Protoc Bioinformatics., 2016, 54, 1.30.1-1.30.33.

Piñero, J.; Queralt-Rosinach, N.; Bravo, A.; Deu-Pons, J.; Bauer-Mehren, A.; Baron, M.; Sanz, F.; Furlong, L.I. DisGeNET: A discovery platform for the dynamical exploration of human diseases and their genes. Database, 2015, 2015, bav028.
[http://dx.doi.org/10.1093/database/bav028] [PMID: 25877637]

Piñero, J.; Ramírez-Anguita, J.M.; Saüch-Pitarch, J.; Ronzano, F.; Centeno, E.; Sanz, F.; Furlong, L.I. The DisGeNET knowledge platform for disease genomics: 2019 update. Nucleic Acids Res., 2020, 48(D1), D845-D855.
[PMID: 31680165]

Sherman, B.T.; Hao, M.; Qiu, J.; Jiao, X.; Baseler, M.W.; Lane, H.C.; Imamichi, T.; Chang, W. DAVID: A web server for functional enrichment analysis and functional annotation of gene lists (2021 update). Nucleic Acids Res., 2022, 50(W1), W216-W221.
[http://dx.doi.org/10.1093/nar/gkac194] [PMID: 35325185]

Szklarczyk, D.; Kirsch, R.; Koutrouli, M.; Nastou, K.; Mehryary, F.; Hachilif, R.; Gable, A.L.; Fang, T.; Doncheva, N.T.; Pyysalo, S.; Bork, P.; Jensen, L.J.; von Mering, C. The STRING database in 2023: Protein–protein association networks and functional enrichment analyses for any sequenced genome of interest. Nucleic Acids Res., 2023, 51(D1), D638-D646.
[http://dx.doi.org/10.1093/nar/gkac1000] [PMID: 36370105]

Bai, G.; Pan, Y.; Zhang, Y.; Li, Y.; Wang, J.; Wang, Y.; Teng, W.; Jin, G.; Geng, F.; Cao, J. Research advances of molecular docking and molecular dynamic simulation in recognizing interaction between muscle proteins and exogenous additives. Food Chem., 2023, 429, 136836.
[http://dx.doi.org/10.1016/j.foodchem.2023.136836] [PMID: 37453331]

Crampon, K.; Giorkallos, A.; Deldossi, M.; Baud, S.; Steffenel, L.A. Machine-learning methods for ligand–protein molecular docking. Drug Discov. Today, 2022, 27(1), 151-164.
[http://dx.doi.org/10.1016/j.drudis.2021.09.007] [PMID: 34560276]

Pinzi, L.; Rastelli, G. Molecular docking: Shifting paradigms in drug discovery. Int. J. Mol. Sci., 2019, 20(18), 4331.
[http://dx.doi.org/10.3390/ijms20184331] [PMID: 31487867]

Wang, Q.; Lin, J.; Li, C.; Lin, M.; Zhang, Q.; Zhang, X.; Yao, K. Traditional Chinese medicine method of tonifying kidney for hypertension: Clinical evidence and molecular mechanisms. Front. Cardiovasc. Med., 2022, 9, 1038480.
[http://dx.doi.org/10.3389/fcvm.2022.1038480] [PMID: 36465462]

Xu, Z.; Qian, L.; Niu, R.; Yang, Y.; Liu, C.; Lin, X. Efficacy of huangqi injection in the treatment of hypertensive nephropathy: A systematic review and meta-analysis. Front. Med., 2022, 9, 838256.
[http://dx.doi.org/10.3389/fmed.2022.838256] [PMID: 35547210]

Wu, J.S.; Li, J.M.; Lo, H.Y.; Hsiang, C.Y.; Ho, T.Y. Anti-hypertensive and angiotensin-converting enzyme inhibitory effects of Radix Astragali and its bioactive peptide AM-1. J. Ethnopharmacol., 2020, 254, 112724.
[http://dx.doi.org/10.1016/j.jep.2020.112724] [PMID: 32119952]

Li, N.Y.; Yu, H.; Li, X.L.; Wang, Q.Y.; Zhang, X.W.; Ma, R.X.; Zhao, Y.; Xu, H.; Liang, W.; Bai, F.; Yu, J. Astragalus membranaceus improving asymptomatic left ventricular diastolic dysfunction in postmenopausal hypertensive women with metabolic syndrome. Chin. Med. J., 2018, 131(5), 516-526.
[http://dx.doi.org/10.4103/0366-6999.226077] [PMID: 29483384]

Hu, J.Y.; Han, J.; Chu, Z.G.; Song, H.P.; Zhang, D.X.; Zhang, Q.; Huang, Y.S. Astragaloside IV attenuates hypoxia-induced cardiomyocyte damage in rats by upregulating superoxide dismutase-1 levels. Clin. Exp. Pharmacol. Physiol., 2009, 36(4), 351-357.
[http://dx.doi.org/10.1111/j.1440-1681.2008.05059.x] [PMID: 18986331]

Tan, Y.Q.; Chen, H.W.; Li, J.; Astragaloside, I.V.; Astragaloside, I.V. An effective drug for the treatment of cardiovascular diseases. Drug Des. Devel. Ther., 2020, 14, 3731-3746.
[http://dx.doi.org/10.2147/DDDT.S272355] [PMID: 32982178]

Wegiel, B.; Persson, J.L. Effect of a novel botanical agent drynol cibotin on human osteoblast cells and implications for osteoporosis: Promotion of cell growth, calcium uptake and collagen production. Phytother. Res., 2010, 24(S2), S139-S147.
[http://dx.doi.org/10.1002/ptr.3026] [PMID: 19953582]

Li, S.; Nong, Y.; Gao, Q.; Liu, J.; Li, Y.; Cui, X.; Wan, J.; Lu, J.; Sun, M.; Wu, Q.; Shi, X.; Cui, H.; Liu, W.; Zhou, M.; Li, L.; Lin, Q. Astragalus granule prevents Ca 2+ current remodeling in heart failure by the downregulation of CaMKII. Evid. Based Complement. Alternat. Med., 2017, 2017, 1-10.
[http://dx.doi.org/10.1155/2017/7517358] [PMID: 28855948]

Jin, G.Z.; Na, Y.; Hua, H.; Guang, H.W.; Dong, S.G.; Xiao, L.W.; Xue, Z.W.; Guang, Y.S. Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure. Chin. J. Integr. Med., 2005, 11(3), 187-190.
[http://dx.doi.org/10.1007/BF02836502] [PMID: 16181532]

Ma, J.; Peng, A.; Lin, S. Mechanisms of the therapeutic effect of Astragalus membranaceus on sodium and water retention in experimental heart failure. Chin. Med. J., 1998, 111(1), 17-23.
[PMID: 10322646]

Montenegro, M.F.; Neto-Neves, E.M.; Dias-Junior, C.A.; Ceron, C.S.; Castro, M.M.; Gomes, V.A.; Kanashiro, A.; Tanus-Santos, J.E. Quercetin restores plasma nitrite and nitroso species levels in renovascular hypertension. Naunyn Schmiedebergs Arch. Pharmacol., 2010, 382(4), 293-301.
[http://dx.doi.org/10.1007/s00210-010-0546-1] [PMID: 20694791]

Guan, Y.; Quan, D.; Chen, K.; Kang, L.; Yang, D.; Wu, H.; Yan, M.; Wu, S.; Lv, L.; Zhang, G. Kaempferol inhibits renal fibrosis by suppression of the sonic hedgehog signaling pathway. Phytomedicine, 2023, 108, 154246.
[http://dx.doi.org/10.1016/j.phymed.2022.154246] [PMID: 36274411]

García-Saura, M.F.; Galisteo, M.; Villar, I.C.; Bermejo, A.; Zarzuelo, A.; Vargas, F.; Duarte, J. Effects of chronic quercetin treatment in experimental renovascular hypertension. Mol. Cell. Biochem., 2005, 270(1-2), 147-155.
[http://dx.doi.org/10.1007/s11010-005-4503-0] [PMID: 15792364]

Machado Dutra, J.; Espitia, P.J.P.; Andrade Batista, R. Formononetin: Biological effects and uses – A review. Food Chem., 2021, 359, 129975.
[http://dx.doi.org/10.1016/j.foodchem.2021.129975] [PMID: 33962193]

Oza, M.J.; Kulkarni, Y.A. Formononetin attenuates kidney damage in type 2 diabetic rats. Life Sci., 2019, 219, 109-121.
[http://dx.doi.org/10.1016/j.lfs.2019.01.013] [PMID: 30641085]

Guo, M.F.; Dai, Y.J.; Gao, J.R.; Chen, P.J. Uncovering the mechanism of astragalus membranaceus in the treatment of diabetic nephropathy based on network pharmacology. J. Diabetes Res., 2020, 2020, 1-13.
[http://dx.doi.org/10.1155/2020/5947304] [PMID: 32215271]

Camarda, N.; Travers, R.; Yang, V.K.; London, C.; Jaffe, I.Z. VEGF receptor inhibitor-induced hypertension: Emerging mechanisms and clinical implications. Curr. Oncol. Rep., 2022, 24(4), 463-474.
[http://dx.doi.org/10.1007/s11912-022-01224-0] [PMID: 35179707]

Feng, Y.; Ye, D.; Wang, Z.; Pan, H.; Lu, X.; Wang, M.; Xu, Y.; Yu, J.; Zhang, J.; Zhao, M.; Xu, S.; Pan, W.; Yin, Z.; Ye, J.; Wan, J. The role of interleukin-6 family members in cardiovascular diseases. Front. Cardiovasc. Med., 2022, 9, 818890.
[http://dx.doi.org/10.3389/fcvm.2022.818890] [PMID: 35402550]

Yin, L.; Bai, J.; Yu, W.J.; Liu, Y.; Li, H.H.; Lin, Q.Y. Blocking VCAM-1 prevents angiotensin II-induced hypertension and vascular remodeling in mice. Front. Pharmacol., 2022, 13, 825459.
[http://dx.doi.org/10.3389/fphar.2022.825459] [PMID: 35222039]

Feng, W.; Guan, Z.; Ying, W.Z.; Xing, D.; Ying, K.E.; Sanders, P.W. Matrix metalloproteinase-9 regulates afferent arteriolar remodeling and function in hypertension-induced kidney disease. Kidney Int., 2023, 104(4), 740-753.
[http://dx.doi.org/10.1016/j.kint.2023.06.031] [PMID: 37423509]

Man, A.W.C.; Zhou, Y.; Reifenberg, G.; Camp, A.; Münzel, T.; Daiber, A.; Xia, N.; Li, H. Deletion of adipocyte NOS3 potentiates high-fat diet-induced hypertension and vascular remodelling via chemerin. Cardiovasc. Res., 2023, 119(17), 2755-2769.
[http://dx.doi.org/10.1093/cvr/cvad164] [PMID: 37897505]

Li, R.; Zhao, A.; Diao, X.; Song, J.; Wang, C.; Li, Y.; Qi, X.; Guan, Z.; Zhang, T.; He, Y. Polymorphism of NOS3 gene and its association with essential hypertension in Guizhou populations of China. PLoS One, 2023, 18(2), e0278680.
[http://dx.doi.org/10.1371/journal.pone.0278680] [PMID: 36758021]

Yu, J.; Wang, S.; Shi, W.; Zhou, W.; Niu, Y.; Huang, S.; Zhang, Y.; Zhang, A.; Jia, Z. Roxadustat prevents Ang II hypertension by targeting angiotensin receptors and eNOS. JCI Insight, 2021, 6(18), e133690.
[http://dx.doi.org/10.1172/jci.insight.133690] [PMID: 34403364]

Szychowski, K.A.; Skóra, B.; Wójtowicz, A.K. Triclosan affects the expression of nitric oxide synthases (NOSs), peroxisome proliferator-activated receptor gamma (PPARγ), and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) in mouse neocortical neurons in vitro. Toxicol. In Vitro, 2021, 73, 105143.
[http://dx.doi.org/10.1016/j.tiv.2021.105143] [PMID: 33722737]

Sandes, E.O.; Lodillinsky, C.; Langle, Y.; Belgorosky, D.; Marino, L.; Gimenez, L.; Casabé, A.R.; Eiján, A.M. Inducible nitric oxide synthase and PPARγ are involved in bladder cancer progression. J. Urol., 2012, 188(3), 967-973.
[http://dx.doi.org/10.1016/j.juro.2012.04.099] [PMID: 22819108]

Yuen, C.Y.; Wong, W.T.; Tian, X.Y.; Wong, S.L.; Lau, C.W.; Yu, J.; Tomlinson, B.; Yao, X.; Huang, Y. Telmisartan inhibits vasoconstriction via PPARγ-dependent expression and activation of endothelial nitric oxide synthase. Cardiovasc. Res., 2011, 90(1), 122-129.
[http://dx.doi.org/10.1093/cvr/cvq392] [PMID: 21156825]

Vallée, A.; Lévy, B.L.; Blacher, J. Interplay between the renin-angiotensin system, the canonical WNT/β-catenin pathway and PPARγ in hypertension. Curr. Hypertens. Rep., 2018, 20(7), 62.
[http://dx.doi.org/10.1007/s11906-018-0860-4] [PMID: 29884931]

Sigmund, C.D. A clinical link between peroxisome proliferator-activated receptor γ and the renin-angiotensin system. Arterioscler. Thromb. Vasc. Biol., 2013, 33(4), 676-678.
[http://dx.doi.org/10.1161/ATVBAHA.112.301125] [PMID: 23486770]

Fang, S.; Livergood, M.C.; Nakagawa, P.; Wu, J.; Sigmund, C.D. Role of the peroxisome proliferator activated receptors in hypertension. Circ. Res., 2021, 128(7), 1021-1039.
[http://dx.doi.org/10.1161/CIRCRESAHA.120.318062] [PMID: 33793338]

Kökény, G.; Calvier, L.; Hansmann, G. PPARγ and TGFβ—major regulators of metabolism, inflammation, and fibrosis in the lungs and kidneys. Int. J. Mol. Sci., 2021, 22(19), 10431.
[http://dx.doi.org/10.3390/ijms221910431] [PMID: 34638771]

Sonneveld, R.; Hoenderop, J.G.; Isidori, A.M.; Henique, C.; Dijkman, H.B.; Berden, J.H.; Tharaux, P.L.; van der Vlag, J.; Nijenhuis, T. Sildenafil prevents podocyte injury via PPAR-γ–mediated TRPC6 inhibition. J. Am. Soc. Nephrol., 2017, 28(5), 1491-1505.
[http://dx.doi.org/10.1681/ASN.2015080885] [PMID: 27895156]

Ma, Y.; Shi, M.; Wang, Y.; Liu, J. PPAR γ and its agonists in chronic kidney disease. Int. J. Nephrol., 2020, 2020, 1-10.
[http://dx.doi.org/10.1155/2020/2917474] [PMID: 32158560]

Anwar, M.A.; Shalhoub, J.; Lim, C.S.; Gohel, M.S.; Davies, A.H. The effect of pressure-induced mechanical stretch on vascular wall differential gene expression. J. Vasc. Res., 2012, 49(6), 463-478.
[http://dx.doi.org/10.1159/000339151] [PMID: 22796658]