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Current Drug Safety

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ISSN (Print): 1574-8863
ISSN (Online): 2212-3911

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Review Article

Unveiling the Latest Breakthroughs: A Comprehensive Review of the Therapeutic Activity and Safety Profile of Aloe vera

Author(s): Alimuddin Saifi*, Alok Sharma, Anurag Chaudhary, Nazia Siddiqui, Vrish Dhwaj Ashwlayan and Bhuwanendra Singh

Volume 19, Issue 4, 2024

Published on: 09 January, 2024

Page: [407 - 416] Pages: 10

DOI: 10.2174/0115748863274759231221093309

Price: $65

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Abstract

The use of herbal drugs as alternative and complementary medicine has increased in popularity, raising concerns about their safety profile. Aloe vera, a plant with diverse therapeutic properties, has been extensively used for centuries. This review aims to assess the therapeutic activity and safety profile of Aloe vera. A comprehensive literature search was conducted to gather relevant information from various biomedical databases. The chemical composition, mechanism of action, and therapeutic activities of Aloe vera were analyzed. Aloe vera contains numerous active components such as vitamins, enzymes, minerals, sugars, lignin, saponins, and anthraquinones. Its mechanisms of action involve collagen synthesis, anti-inflammatory effects, immune modulation, laxative properties, and antiviral activity. Aloe vera has demonstrated potential therapeutic benefits in wound healing, diabetes management, liver and kidney protection, and glycemic control. However, it is essential to consider potential side effects, such as skin irritation and allergic reactions. This review provides evidence-based information to improve patient safety and promote informed decisions regarding the use of Aloe vera as a therapeutic agent.

Keywords: Aloe vera, therapeutic activity, safety profile, herbal medicine, cellulose, lipase.

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