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Current Organic Chemistry

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ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

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Mini-Review Article

Various Synthetic Methods and Diverse Therapeutic Potential of Substituted Thiazine Derivatives

Author(s): Mohammad Asif*, Mamdouh Allahyani, Ahad Amer Alsaiari and Mazen Mohammed Almehmadi

Volume 27, Issue 20, 2023

Published on: 27 November, 2023

Page: [1741 - 1753] Pages: 13

DOI: 10.2174/0113852728260166231101070430

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Abstract

Heterocyclic compounds are currently of great interest in pharmaceutical research. Many natural products, including vitamins, hormones, and antibiotics, contain heterocyclic compounds, and these substances have grown in importance. Heterocyclic thiazine derivatives have numerous pharmacological actions, including anticancer, antimicrobial, antipsychotic, anti-mycobacterial, anti-fungal, antiviral, antimycobacterial, antioxidant, analgesic, antipyretic, anti-inflammatory activities, which is present in numerous substances. The N-CS linkage in its scaffold and the ease and economy of its synthesis methods have been key factors in the development of these molecules. Recently, numerous studies considering the various biological actions of thiazines have been published. Thiazine, a six-membered heterocyclic compound with nitrogen and sulfur in its ring system, has a wide range of chemical possibilities, which has encouraged insistent research into their various synthesis processes. The current review focuses on thiazine derivatives with potential biological activities.

Keywords: Thiazines, pharmacological activities, antimicrobial, analgesic, anti-inflammatory, anticancer, antipsychotic agent.

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