Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding

Antonio      Pesce; Valentina      Sani; Alba      Gaban; Nicolò      Fabbri; Massimo      Tilli; Roberta      Gafà; Carlo   Vittorio   Feo

doi:10.2174/0115748928256837231012151452

Abstract

Background: Intracholecystic papillary neoplasms (ICPNs) represent a rare benign entity characterized by intraluminal polypoid lesions in the gallbladder. The incidence of ICPNs ranges from 0.4% to 0.61% in all gallbladder specimens.

Case Presentation: In this report, we present a case of a young Caucasian woman who underwent elective laparoscopic cholecystectomy due to gallbladder polyps. The histological examination revealed the presence of an intracholecystic papillary neoplasm (ICPN) with a tubulopapillary growth pattern, exhibiting gastric morphology and displaying both low and high-grade dysplasia. A thorough review of the existing literature was conducted, with a specific focus on the histological features.

Conclusion: A comprehensive understanding of neoplastic polyps of the gallbladder is still limited. Pathological examination of these lesions is crucial for identifying key features that can influence patient outcomes and survival.

Keywords: Gallbladder polyps, laparoscopic cholecystectomy, papillary-tubular neoplasm, pathological study ICPN, premalignant gallbladder, specimens.

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DOI https://dx.doi.org/10.2174/0115748928256837231012151452	Print ISSN 1574-8928
Publisher Name Bentham Science Publisher	Online ISSN 2212-3970

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Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding

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