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Current Medical Imaging

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ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

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Case Report

Establishment and Comparison of Piecewise Linear Regression Models to Measure Thyroid Volume by 2D and 3D Ultrasound

Author(s): Yue-Gui Wang, Shu-Ping Yang, Ming-Yong Cai, Ke-Yue Chen, Ting-Ting Li and Hao-Lin Shen*

Volume 20, 2024

Published on: 23 October, 2023

Article ID: e080923220831 Pages: 6

DOI: 10.2174/1573405620666230908111821

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Abstract

Objective: Compared thyroid volumes measured by 2-D and 3-D US with those of resected specimens and proposed new models to improve measurement accuracy.

Methods: This study included 80 patients who underwent total thyroidectomy. One 2D_model and one 3D_model were developed using piecewise linear regression analysis. The accuracy of these models was compared using an ellipsoid model (2-D_US value × 0.5), 3-D_US value, and Ying’s model [1.76 + (2-D_US value × 0.38)].

Results: The new 2D_model was: V=2.66 + (0.71 * X1) - (1.51 * X2). In this model, if 2-D_US value <= 228.39, X1 = 2-D_US value and X2 = 0; otherwise, X1 = 2-D_US value and X2 = 2-D_US value - 228.39. The 3D_model was: V= 2.90 + (1.08 * X1) + (2.43 * X2). In this model, if 3- D_US value <= 102.06, X1 = 3-D_US value and X2 = 0; otherwise, X1 = 3-D_US value and X2 = 3-D_US value - 102.06. The accuracy of the new models was higher than that of the 3-D_US value, the ellipsoid model, and Ying’s model (P<0.05).

Conclusion: The models established are more accurate than the traditional ones and can accurately measure thyroid volume.

Keywords: Thyroid volume, Piecewise linear regression model, Ultrasound, Thyroid morphology, Graves’ disease.

[1]
Lee SJ, Chong S, Kang KH, et al. Semiautomated thyroid volumetry using 3D CT: prospective comparison with measurements obtained using 2D ultrasound, 2D CT, and water displacement method of specimen. AJR Am J Roentgenol 2014; 203: 525-32.
[2]
Ng SM, Turner MA, Avula S. Ultrasound Measurements of Thyroid Gland Volume at 36 Weeks’ Corrected Gestational Age in Extremely Preterm Infants Born before 28 Weeks’. Gestation Eur Thyroid J 2018; 7: 21-6.
[3]
Bauman WA, Wecht JM, Biering-Sørensen F. International spinal cord injury endocrine and metabolic extended data set. Spinal Cord 2017; 55: 466-77.
[4]
Souza LRMF, Sedassari NA, Dias EL, et al. Ultrasound measurement of thyroid volume in euthyroid children under 3 years of age. Radiol Bras 2021; 54: 94-8.
[5]
Fujita N, Kato K, Abe S, Naganawa S. Variation in thyroid volumes due to differences in the measured length or area of the cross-sectional plane: A validation study of the ellipsoid approximation method using CT images. J Appl Clin Med Phys 2021; 22: 15-25.
[6]
Liu C, Bi X, Chen Y, Zhou A. Sonography monitoring of thyroid morphology and function in patients with metastatic renal cell carcinoma treated with targeted drugs. Ann Palliat Med 2020; 9: 1577-85.
[7]
Kumar V, Webb J, Gregory A, et al. Automated segmentation of thyroid nodule, gland, and cystic components from ultrasound images using deep learning. IEEE Access 2020; 8: 63482-96.
[8]
Brown MC, Spencer R. Thyroid gland volume estimated by use of ultrasound in addition to scintigraphy. Acta Radiol Oncol Radiat Phys Biol 1978; 17: 337-41.
[9]
Freesmeyer M, Wiegand S, Schierz JH, Winkens T, Licht K. Multimodal evaluation of 2-D and 3-D ultrasound, computed tomography and magnetic resonance imaging in measurements of the thyroid volume using universally applicable cross-sectional imaging software: a phantom study. Ultrasound Med Biol 2014; 40: 1453-62.
[10]
Brunn J, Block U, Ruf G, Bos I, Kunze WP, Scriba PC. Volumetric analysis of thyroid lobes by real-time ultrasound. Dtsch Med Wochenschr 1981; 106: 1338-40.
[11]
Rivas AM, Larumbe-Zabala E, Diaz-Trastoy O, et al. Effect of chemoradiation on the size of the thyroid gland. Proc Bayl Univ Med Cent 2020; 33: 541-5.
[12]
Lyshchik A, Drozd V, Reiners C. Accuracy of three-dimensional ultrasound for thyroid volume measurement in children and adolescents. Thyroid 2004; 14: 113-20.
[13]
Kim SC, Kim JH, Choi SH, et al. Off-site evaluation of three-dimensional ultrasound for the diagnosis of thyroid nodules: comparison with two-dimensional ultrasound. Eur Radiol 2016; 26: 3353-60.
[14]
Azizi G, Faust K, Ogden L, et al. 3-D Ultrasound and Thyroid Cancer Diagnosis: A Prospective Study. Ultrasound Med Biol 2021; 47: 1299-309.
[15]
Ying M, Yung DM, Ho KK. Two-dimensional ultrasound measurement of thyroid gland volume: a new equation with higher correlation with 3-D ultrasound measurement. Ultrasound Med Biol 2008; 34: 56-63.
[16]
Kot BC, Ying MT, Brook FM, Kinoshita RE. Evaluation of two-dimensional and three-dimensional ultrasound in the assessment of thyroid volume of the Indo-Pacific bottlenose dolphin (Tursiops aduncus). J Zoo Wildl Med 2012; 43: 33-49.
[17]
Peduzzi P, Concato J, Feinstein AR, Holford TR. Importance of events per independent variable in proportional hazards regression analysis. II. Accuracy and precision of regression estimates. J Clin Epidemiol 1995; 48: 1503-10.
[18]
Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986; 8: 307-10.
[19]
Shen HL, Yang SP, Wang KJ, et al. Evaluation of gastric blood supply in diabetic patients with gastroparesis by contrast-enhanced ultrasound. Br J Radiol 2016; 89: 366-72.
[20]
Senapati A, Nag A, Mondal A, Maji S. A novel framework for COVID-19 case prediction through piecewise regression in India. Int J Inf Technol 2020; 10: 1-8.

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