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Current Medical Imaging

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ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

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Research Article

Mammography and Ultrasonography Manifestations of Sclerosing Lymphocytic Lobulitis of the Breast: A Series of Seven Case Reports

Author(s): Wanling Lin and Lingyun Bao*

Volume 20, 2024

Published on: 02 October, 2023

Article ID: e040923220675 Pages: 6

DOI: 10.2174/1573405620666230904104346

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Abstract

Objective: The present study aimed to analyze mammography and ultrasonography (US) manifestations of sclerosing lymphocytic lobulitis (SLL) of the breast.

Methods: A total of 8 pathologically confirmed SLL lesions from seven women (with one patient having bilateral breast lesions) were included in the study. All patients underwent preoperative mammography and US examinations. The findings from both modalities were classified and compared to their corresponding clinical data.

Results: Four patients were diagnosed with diabetes mellitus. Mammography results revealed that seven lesions presented as focal asymmetry or asymmetry. Seven lesions were observed as non-mass lesions on US examination. The most commonly observed US lesion features were as follows: seven lesions had focal non-ductal hypoechoic areas (87.5%), seven lesions exhibited posterior shadowing (87.5%), all lesions showed no vascularity or vessels in the rim (100%), no lesion had calcifications (0%), five lesions had an elasticity score of 3 (100%), one lesion showed retraction on the coronal plane (20%), and one lesion displayed a skipping sign on the coronal plane (20%). Based on these US findings, seven lesions (87.5%) were classified as BI-RADS 4.

Conclusion: The mammography findings for SLL are often nonspecific. However, the US features of SLL typically present as non-mass lesions. The absence of calcification and vascularity and no retraction on the coronal plane inside the lesion may help to differentiate this disease from the conventional forms of breast carcinoma.

Keywords: Sclerosing lymphocytic lobulitis of breast, Ultrasonography, Mammography, Vasculitis, Benign breast.

[1]
Miralles TG, Gosalbez F, Menendez P, Manjon JA, Sampedro A. Fine needle aspiration of sclerosing lymphocytic lobulitis of the breast. A report of two cases. Acta Cytol 1998; 42(6): 1447-50.
[http://dx.doi.org/10.1159/000332184] [PMID: 9850659]
[2]
Martínez-Ramos D, Alcalde-Sánchez M, Laguna-Sastre M, Rodríguez-Pereira C, Artero-Sempere R, Salvador-Sanchís JL. Mastopatía diabética. Estudio de 4 pacientes. Cir Esp 2007; 81(4): 224-6.
[http://dx.doi.org/10.1016/S0009-739X(07)71305-2] [PMID: 17403361]
[3]
Suvannarerg V, Claimon T, Sitthinamsuwan P, Thiravit S, Muangsomboon K, Korpraphong P. Clinical, mammographic, and ultrasonographic characteristics of diabetic mastopathy: A case series. Clin Imaging 2019; 53: 204-9.
[http://dx.doi.org/10.1016/j.clinimag.2018.11.002] [PMID: 30423508]
[4]
Soler N, Khardori R. Fibrous disease of the breast, thyroiditis, and cheiroarthropathy in type I diabetes mellitus. Lancet 1984; 323(8370): 193-5.
[http://dx.doi.org/10.1016/S0140-6736(84)92114-7] [PMID: 6141337]
[5]
Leroux-Stewart J, Rabasa-Lhoret R. Diabetic mastopathy: Case report and summary of literature. Can J Diabetes 2014; 38(5): 305-6.
[http://dx.doi.org/10.1016/j.jcjd.2013.12.008] [PMID: 24821390]
[6]
D’Orsi C, Morris E, Mendelson E. ACR BI-RADS® Atlas. Breast Imaging Reporting and Data System 2013.
[7]
Itoh A, Ueno E, Tohno E, et al. Breast disease: Clinical application of US elastography for diagnosis. Radiology 2006; 239(2): 341-50.
[http://dx.doi.org/10.1148/radiol.2391041676] [PMID: 16484352]
[8]
Kim J, Kim EK, Kim MJ, Moon HJ, Yoon JH. Diabetic mastopathy: Imaging features and the role of image-guided biopsy in its diagnosis. 2016; 35(2): 140-7.
[http://dx.doi.org/10.14366/usg.15052] [PMID: 26810194]
[9]
Oztekin PS, Karatas B, Ugur S, Kosar PN, Erel S, Borcek P. Sclerosing lymphocytic lobulitis in the absence of diabetes or autoimmune disease: radiological findings. Breast J 2014; 20(6): 655-7.
[http://dx.doi.org/10.1111/tbj.12343] [PMID: 25252167]
[10]
Sato LT, de Mello GGN, Stiepcich MMA, et al. Ultrasound as a valuable imaging modality in sclerosing lymphocytic lobulitis: Imaging features based on a retrospective cohort analysis of 51 cases. Can Assoc Radiol J 2021; 72(4): 767-74.
[http://dx.doi.org/10.1177/0846537120983122] [PMID: 33461324]
[11]
Guzik P, Gęca T, Topolewski P, et al. Diabetic mastopathy. Review of diagnostic methods and therapeutic options. Int J Environ Res Public Health 2021; 19(1): 448.
[http://dx.doi.org/10.3390/ijerph19010448] [PMID: 35010708]
[12]
Chen XX, Shao SJ, Wan H. Diabetic mastopathy in an elderly woman misdiagnosed as breast cancer: A case report and review of the literature. World J Clin Cases 2021; 9(14): 3458-65.
[http://dx.doi.org/10.12998/wjcc.v9.i14.3458] [PMID: 34002158]
[13]
Mandelson MT, Oestreicher N, Porter PL, et al. Breast density as a predictor of mammographic detection: Comparison of interval- and screen-detected cancers. J Natl Cancer Inst 2000; 92(13): 1081-7.
[http://dx.doi.org/10.1093/jnci/92.13.1081] [PMID: 10880551]
[14]
Wood E, Propeck P. Atypical sonographic presentation of diabetic mastopathy: A case report and literature review. J Clin Imaging Sci 2021; 11: 60.
[http://dx.doi.org/10.25259/JCIS_111_2021]
[15]
Park SH, Choi SJ, Jung HK. Sclerosing lymphocytic lobulitis manifesting as suspicious microcalcifications with hashimoto's thyroiditis in a young woman. Breast J 2013; 19(5)
[http://dx.doi.org/10.1111/tbj.12156] [PMID: 23834442]
[16]
Dipiro PJ, Meyer JE, Lester SC. An unusual presentation of lymphocytic mastopathy in a diabetic patient. Clin Radiol 1999; 54(12): 845-6.
[http://dx.doi.org/10.1016/S0009-9260(99)90691-8] [PMID: 10619304]
[17]
Moschetta M, Telegrafo M, Triggiani V, et al. Diabetic mastopathy: A diagnostic challenge in breast sonography. J Clin Ultrasound 2015; 43(2): 113-7.
[http://dx.doi.org/10.1002/jcu.22246] [PMID: 25327165]
[18]
Andrews-Tang D, Diamond AB, Rogers L, Butler D. Diabetic mastopathy: Adjunctive use of ultrasound and utility of core biopsy in diagnosis. Breast J 2000; 6(3): 183-8.
[http://dx.doi.org/10.1046/j.1524-4741.2000.99073.x] [PMID: 11348362]
[19]
Thanarajasingam U, Chen B, Tortorelli CL, Jakub JW, Ghosh K. Diabetic mastopathy as a radiographically occult palpable breast mass. Case Rep Med 2011; 2011: 162350.
[http://dx.doi.org/10.1155/2011/162350] [PMID: 22110508]

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