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Current Medical Imaging

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ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

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Research Article

Radiological Features of Rare Non-odontogenic Lesions of the Jaws

Author(s): Murat Akkoyunlu*, Emre Bulgurcu*, Cagrı Delilbası and Nuran Sabir

Volume 20, 2024

Published on: 19 October, 2023

Article ID: e010923220609 Pages: 13

DOI: 10.2174/1573405620666230901102904

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Abstract

Background: The jaws can be affected by several lesions that manifest in the oral cavity, but little is known about non-odontogenic benign and malignant lesions and their radiological findings.

Introduction: Our aim was to discuss the imaging findings of non-odontogenic jaw lesions to help the surgeon in the diagnosis and formulating a differential diagnosis for this vast spectrum of jaw lesions with overlapping clinical and imaging appearances.

Methods: CT and MR images of the mandible, maxillofacial region, and neck were retrieved from the archive of the Radiology Department of Pamukkale University for the duration between 2012-2023 and assessed.

Results: A total of 8125 CT and MR images were retrospectively analyzed. The mean age of the patients was 39.5 years in females and 43.2 in males, with a range varying from 15 to 72 years. Histopathologically approved benign and malignant non-odontogenic lesions were detected in only 19 patients out of 8125 images (0.23%). Osteomyelitis and abscess were the most common (n=3; 0.03%), followed by two cases (n=2; 0.02%) of each fibrous dysplasia, hemangioma, osteosarcoma, squamous cell carcinoma, and multiple myeloma, and one case (n=1; 0.01%) of each ossifying fibroma, osteoma, lymphoma, metastasis, and solitary bone cyst.

Conclusion: Although non-odontogenic benign and malignant lesions of the jaw are rare, awareness of the radiological features of these lesions plays an important role in their diagnosis and management.

Keywords: Non-odontogenic lesions, Jaw, Radiological findings, Computed tomography, Magnetic resonance, multiple myeloma, Osteomyelitis.

[1]
Curé JK, Vattoth S, Shah R. Radiopaque jaw lesions: An approach to the differential diagnosis. Radiographics 2012; 32(7): 1909-25.
[http://dx.doi.org/10.1148/rg.327125003] [PMID: 23150848]
[2]
Koenig LJ, Tamimi D, Perschbacher SE. Diagnostic Imaging: Oral and Maxillofacial E-Book. Elsevier Health Sciences 2017.
[3]
Fonseca LC, Kodama NK, Nunes FCF, et al. Radiographic assessment of Gardner’s syndrome. Dentomaxillofac Radiol 2007; 36(2): 121-4.
[http://dx.doi.org/10.1259/dmfr/18554322] [PMID: 17403893]
[4]
Kaplan I, Nicolaou Z, Hatuel D, Calderon S. Solitary central osteoma of the jaws: A diagnostic dilemma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008; 106(3): e22-9.
[http://dx.doi.org/10.1016/j.tripleo.2008.04.013] [PMID: 18602294]
[5]
Eversole R, Su L, ElMofty S. Benign fibro-osseous lesions of the craniofacial complex. A review. Head Neck Pathol 2008; 2(3): 177-202.
[http://dx.doi.org/10.1007/s12105-008-0057-2] [PMID: 20614314]
[6]
Coleman H, Hille J, Van Heerden W, Boy S, Mahar A. Non-odontogenic bone pathology. Contemporary Oral Medicine. Springer 2018.
[7]
Collins MT, Singer FR, Eugster E. McCune-Albright syndrome and the extraskeletal manifestations of fibrous dysplasia. Orphanet J Rare Dis 2012; 7(S1): S4.
[http://dx.doi.org/10.1186/1750-1172-7-S1-S4] [PMID: 22640971]
[8]
Abdelkarim A, Green R, Startzell J, Preece J. Craniofacial polyostotic fibrous dysplasia: A case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008; 106(1): e49-55.
[http://dx.doi.org/10.1016/j.tripleo.2008.03.023] [PMID: 18585612]
[9]
Faivre L, Nivelon-Chevallier A, Kottler ML, et al. Mazabraud syndrome in two patients: Clinical overlap with McCune-Albright syndrome. Am J Med Genet 2001; 99(2): 132-6.
[http://dx.doi.org/10.1002/1096-8628(2000)9999:999<00::AID-AJMG1135>3.0.CO;2-A] [PMID: 11241472]
[10]
MacDonald-Jankowski DS. Fibro-osseous lesions of the face and jaws. Clin Radiol 2004; 59(1): 11-25.
[http://dx.doi.org/10.1016/j.crad.2003.07.003] [PMID: 14697371]
[11]
Chandra SR, Chen E, Cousin T, Oda D. A case series of intraosseous hemangioma of the jaws: Various presentations of a rare entity. J Clin Exp Dent 2017; 9(11): 0.
[http://dx.doi.org/10.4317/jced.54285] [PMID: 29302291]
[12]
Dhiman N, Jaiswara C, Kumar N, Patne SU, Pandey A, Verma V. Central cavernous hemangioma of mandible: Case report and review of literature. Natl J Maxillofac Surg 2015; 6(2): 209-13.
[http://dx.doi.org/10.4103/0975-5950.183866] [PMID: 27390499]
[13]
Gómez E, González T, Arias J, Lasaletta L. Three-dimensional reconstruction after removal of zygomatic intraosseous hemangioma. Oral Maxillofac Surg 2008; 12(3): 159-62.
[http://dx.doi.org/10.1007/s10006-008-0115-7] [PMID: 18636281]
[14]
Jadaun G, Bindra S, Jois H, Sen P. Traumatic bone cyst of mandible: A case report of rare entity and review of literature. Contemp Clin Dent 2019; 10(1): 3-8.
[http://dx.doi.org/10.4103/ccd.ccd_489_18] [PMID: 32015634]
[15]
Sabino-Bezerra JR, Santos-Silva AR, Jorge J Jr, Gouvêa AF, Lopes MA. Atypical presentations of simple bone cysts of the mandible: A case series and review of literature. J Craniomaxillofac Surg 2013; 41(5): 391-6.
[http://dx.doi.org/10.1016/j.jcms.2012.11.002] [PMID: 23218982]
[16]
Avril L, Lombardi T, Ailianou A, et al. Radiolucent lesions of the mandible: A pattern-based approach to diagnosis. Insights Imaging 2014; 5(1): 85-101.
[http://dx.doi.org/10.1007/s13244-013-0298-9] [PMID: 24323536]
[17]
Dunfee BL, Sakai O, Pistey R, Gohel A. Radiologic and pathologic characteristics of benign and malignant lesions of the mandible. Radiographics 2006; 26(6): 1751-68.
[http://dx.doi.org/10.1148/rg.266055189] [PMID: 17102048]
[18]
Nezafati S, Ghavimi MA, Yavari AS. Localized osteomyelitis of the mandible secondary to dental treatment: Report of a case. J Dent Res Dent Clin Dent Prospect 2009; 3(2): 67-9.
[PMID: 23230486]
[19]
Eldaya R, Eissa O, Herrmann S, Pham J, Calle S, Uribe T. Mandibular Lesions. Contemp Diagn Radiol 2017; 40(6): 1-7.
[http://dx.doi.org/10.1097/01.CDR.0000513197.01378.d8]
[20]
MacDonald-Jankowski DS. Ossifying fibroma: A systematic review. Dentomaxillofac Radiol 2009; 38(8): 495-513.
[http://dx.doi.org/10.1259/dmfr/70933621] [PMID: 20026707]
[21]
Trotta BM, Pease CS, Rasamny JJ, Raghavan P, Mukherjee S. Oral cavity and oropharyngeal squamous cell cancer: key imaging findings for staging and treatment planning. Radiographics 2011; 31(2): 339-54.
[http://dx.doi.org/10.1148/rg.312105107] [PMID: 21415183]
[22]
Jimi E, Furuta H, Matsuo K, Tominaga K, Takahashi T, Nakanishi O. The cellular and molecular mechanisms of bone invasion by oral squamous cell carcinoma. Oral Dis 2011; 17(5): 462-8.
[http://dx.doi.org/10.1111/j.1601-0825.2010.01781.x] [PMID: 21496184]
[23]
Park HK, Kim TS, Geum DH, et al. Mandibular intraosseous squamous cell carcinoma lesion associated with odontogenic keratocyst: A case report. J Korean Assoc Oral Maxillofac Surg 2015; 41(2): 78-83.
[http://dx.doi.org/10.5125/jkaoms.2015.41.2.78] [PMID: 25922819]
[24]
Lee RJ, Arshi A, Schwartz HC, Christensen RE. Characteristics and prognostic factors of osteosarcoma of the jaws: A retrospective cohort study. JAMA Otolaryngol Head Neck Surg 2015; 141(5): 470-7.
[http://dx.doi.org/10.1001/jamaoto.2015.0340] [PMID: 25811167]
[25]
Fernandes R, Nikitakis NG, Pazoki A, Ord RA. Osteogenic sarcoma of the jaw: A 10-year experience. J Oral Maxillofac Surg 2007; 65(7): 1286-91.
[http://dx.doi.org/10.1016/j.joms.2006.10.030] [PMID: 17577490]
[26]
Patil A, Nawale KK, Vyas M, Kane S. Metastatic tumors in the jaw bones: A retrospective clinicopathological study of 12 cases at Tertiary Cancer Center. J Oral Maxillofac Pathol 2016; 20(2): 252-5.
[http://dx.doi.org/10.4103/0973-029X.185920] [PMID: 27601818]
[27]
Barnes L. Metastases to the head and neck: An overview. Head Neck Pathol 2009; 3(3): 217-24.
[http://dx.doi.org/10.1007/s12105-009-0123-4] [PMID: 20596975]
[28]
Scolozzi P, Becker M, Lombardi T. Mandibular condylar metastasis mimicking acute internal derangement of the temporomandibular joint. J Can Dent Assoc 2012; 78: c77.
[PMID: 22889503]
[29]
Pisano JJ, Coupland R, Chen SY, Miller AS. Plasmacytoma of the oral cavity and jaws. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997; 83(2): 265-71.
[http://dx.doi.org/10.1016/S1079-2104(97)90015-9] [PMID: 9117760]
[30]
Caggiano M, Di Spirito F, Acerra A, Galdi M, Sisalli L. Multiple-drugs-related osteonecrosis of the jaw in a patient affected by multiple myeloma: A case report. Dent J 2023; 11(4): 104.
[http://dx.doi.org/10.3390/dj11040104] [PMID: 37185482]
[31]
Sharma V, Sharma A. Punched-out lesions in skull. Multiple myeloma. N Z Med J 2010; 123(1312): 81-2.
[PMID: 20389323]
[32]
Bruce KW, Royer RQ. Multiple myeloma occurring in the jaws. Oral Surg Oral Med Oral Pathol 1953; 6(6): 729-44.
[http://dx.doi.org/10.1016/0030-4220(53)90199-6] [PMID: 13063932]
[33]
Mozaffari E, Mupparapu M, Otis L. Undiagnosed multiple myeloma causing extensive dental bleeding: Report of a case and review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002; 94(4): 448-53.
[http://dx.doi.org/10.1067/moe.2002.125201] [PMID: 12374918]
[34]
Ramaiah KKK, Joshi V, Thayi SR, Sathyanarayana P, Patil P, Ahmed Z. Multiple myeloma presenting with a maxillary lesion as the first sign. Imaging Sci Dent 2015; 45(1): 55-60.
[http://dx.doi.org/10.5624/isd.2015.45.1.55] [PMID: 25793184]
[35]
Gonzalez-Fontal GR, Rosales JD, Jaramillo R, Henao-Martinez AF. Primary extranodal, extralymphatic hodgkin lymphoma of the mandible. Case Rep Med 2011; 2011: 1-4.
[http://dx.doi.org/10.1155/2011/387570] [PMID: 21765842]
[36]
Imaizumi A, Kuribayashi A, Watanabe H, et al. Non-Hodgkin lymphoma involving the mandible: Imaging findings. Oral Surg Oral Med Oral Pathol Oral Radiol 2012; 113(5): e33-9.
[http://dx.doi.org/10.1016/j.oooo.2011.10.004] [PMID: 22668637]
[37]
Terzic A, Becker M, Imholz B, Scolozzi P. Unilateral widening of the inferior alveolar nerve canal: A rare anatomic variant mimicking disease. Oral Radiol 2013; 29(2): 160-5.
[http://dx.doi.org/10.1007/s11282-012-0118-9]

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