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Review Article

卡唑类三环类化合物抗癌活性研究进展

卷 31, 期 30, 2024

发表于: 25 August, 2023

页: [4826 - 4849] 页: 24

弟呕挨: 10.2174/0929867331666230825104254

价格: $65

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摘要

癌症是对人类生命和健康的巨大威胁。每年都有许多人患各种癌症，并死于各种癌症，许多资源被用于对抗癌症。由于抗癌药物的一些缺点，如药物引起的副作用，耐药性等，它们在征服癌症的能力上仍有很大的差距。因此，迫切需要发现和开发许多新的化学型来抑制癌症。本文主要综述了两种具有代表性的咔唑类化合物:咔啉衍生物和重氮咔唑衍生物的抗癌作用。尚未被充分开发的双氮咔唑衍生物可能会给我们带来新的视野和宝贵的机会，以克服我们目前在抗癌运动中面临的巨大障碍。我们还提供了几种合成方法来构建咔唑基三环化合物的关键骨架。

关键词: 抗癌，耐药，卡波林，重氮咔唑，卡波唑类化合物，化学型。

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