摘要
在许多情况下,神经防御系统的一些关键因素失效,慢慢导致神经退行性疾病。通过施用外源性药物来抵消不利的变化,激活这一自然过程似乎是有希望的。因此,寻找神经保护疗法,我们必须把重点放在抑制导致神经元损伤的主要机制的化合物上,例如细胞凋亡、兴奋性毒性、氧化应激和炎症。在许多被认为是神经保护剂的化合物中,从天然材料中提取的蛋白质水解物和肽或其合成类似物是很好的候选物。它们具有选择性和生物活性高、靶点范围广、安全性高等优点。本文综述了植物源性蛋白水解物和多肽的生物活性、作用机制和功能特性。我们专注于它们在人类健康中的重要作用,通过影响神经系统,具有神经保护和大脑促进特性,导致记忆和认知改善活动。我们希望我们的观察结果可以指导具有潜在神经保护作用的新型肽的评估。对神经保护肽的研究可以在不同领域找到应用,作为功能性食品或药物的成分,以改善人类健康和预防疾病。
关键词: 植物源性材料,神经保护,神经退行性疾病,氧化应激,食物摄入,生物活性肽,抗氧化剂,水解产物。
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