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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

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Biography

Meet the Editorial Board Member

Author(s): Nageswara R. Desaboini

Volume 30, Issue 20, 2023

Published on: 01 March, 2023

Page: [2225 - 2225] Pages: 1

DOI: 10.2174/092986733020230301144832

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[1]
Jacqueto, Z.; Desaboini, N.R.; Colby, J.; Ala, M.S.; Ellen, A.N.; Aria, J.; Nese, K.Y.; Akbar, A.; Celia, A.S. Allosteric quinoxaline-based inhibitors of the flavivirus NS2B-NS3 protease. Bioorg. Chem., 2023, 131, 106269.
[2]
Desaboini, N.R.; Xincai, J.; Stephen, C.M. Silicon functionalization expands the repertoire of Si-rhodamine fluorescent probes. Chem. Sci., 2022, 13, 6081-6088.
[3]
Jacqueto, Z.; Desaboini, N.R.; Sang, V.V.; Mina, H.; Klajdi, K.; Ashley, N.M.; Elise, C.; Akbar, A.; Nese, K.Y.; Celia, A.S. Deciphering the molecular mechanism and role of fluorination in HCV protease inhibitor potency and drug resistance. J. Mol. Biol., 2022, 434, 167503.
[4]
Desaboini, N.R.; Jacqueto, Z.; Mina, H.; Elise, T.C.; Ashley, N.M.; Adam, K.H.; Hasahn, L.C.; Mohsan, S.; Alicia, N.; Christos, J.P.; Wei, H.; Nese, K.Y.; Celia, A.S.; Akbar, A. Discovery of quinoxaline-based P1-P3 macrocyclic NS3/4A protease inhibitors with potent activity against drug-resistant hepatitis C virus variants. J. Med. Chem., 2021, 64, 11972-11989.
[5]
Ajesh, V.; Desaboini, N.R.; Radhakrishnan, K.V.; Partick, Y.S.L.; Parthasarathi, D. Advances in carbon–element bond construction under chan–lam cross-coupling conditions: A second decade. Synthesis, 2021, 53, 805-847.
[6]
Linah, N.R.; Gordon, J.L.; Mina, H. Sook-Kyung; L.; Ean, S.; Desaboini, N.R.; Klajdi, K.; Ellen, A.N.; Ronald, S.; Nese, K.Y., Celia, A.S.; Akbar A. structural analysis of potent hybrid HIV-1 protease inhibitors containing bis-tetrahydrofuran in a pseudosymmetric dipeptide isostere. J. Med. Chem., 2020, 63, 8296-8313.
[7]
Ashley, N.M.; Jacqueto, Z.; Desaboini, N.R.; Mina, H.; Wasih, K.; Klajdi, K.; Adam, K.H.; Gordon, J.L.; Jennifer, T.; Akbar, A.; Nese, K.Y.; Celia, A.S. Avoiding drug resistance by substrate envelope-guided design: toward potent and robust HCV NS3/4A protease inhibitors. mBio March, 2020, 11, e00172-e20.
[8]
Desaboini, N.R.; Rasheed, S.; Gaurav, R.; Qazi, N.A.; Chaitanya, K.J.; Prasad, V.B.; Parthasarathi, D. Cobalt-catalyzed regioselective ortho C(sp2)-H bond nitration of aromatics through proton-coupled electron transfer assistance. J. Org. Chem., 2017, 82, 7234-7244.
[9]
Reddy, S.; Kumar, K.R.; Desaboini, N.R.; Partick, Y.S.L.; Parthasarathi, D. Copper (II)-catalyzed chan-lam cross-coupling: Chemose-lective N-arylation of aminophenols. Org. Biomol. Chem., 2017, 15, 801-806.
[10]
Desaboini, N.R.; Rasheed, S.; Parthasarathi, D. Palladium/silver synergistic catalysis in direct aerobic carbonylation of C(sp2)-H bonds using DMF as a carbon source: Synthesis of pyrido-fused quinazolinones and phenanthridinones. Org. Lett., 2016, 18, 3142-3145.

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