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Review Article

黑素皮质素受体:治疗色素沉着、炎症、压力、体重障碍和性功能障碍的新兴靶点

卷 24, 期 2, 2023

发表于: 25 November, 2022

页: [151 - 156] 页: 6

弟呕挨: 10.2174/1389450124666221108143006

价格: $65

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摘要

黑素皮质素是原黑素皮质素翻译后裂解形成的微小蛋白质分子。这些是生物活性肽，负责人类和低等动物的色素沉着模式、能量稳态和性功能调节。这些肽通过在中枢神经系统和外周组织中产生来调节许多生理功能。根据最近的研究，黑素皮质素通过结合到一个单独的G蛋白家族，两种主要的蛋白水解酶，原转化酶1和2来引发它们的各种生物效应。这些突破为研究黑素皮质素、拮抗剂和受体在许多生理活动中的作用开辟了新的途径。

关键词: 黑素皮质素受体，刺豚鼠相关肽，原黑素皮质素，黑色素素，色素沉着治疗，黑色素

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图形摘要

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