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Review Article

小脑中癫痫的深入研究:神经解剖学和细胞方法

卷 30, 期 32, 2023

发表于: 27 December, 2022

页: [3630 - 3648] 页: 19

弟呕挨: 10.2174/0929867330666221028150138

价格: $65

Open Access Journals Promotions 2
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摘要

目的：本文的目的是描述癫痫患者小脑的神经解剖学和细胞方面的最新进展。 背景：多年来，小脑癫痫发生已被广泛研究。越来越多的证据表明，小脑与这一病理有关的几个其他结构:主要是边缘系统、丘脑、大脑皮层、红核和网状结构。因此，小脑的这些解剖和细胞变化可能引发癫痫发作的发生和传播。 讨论：在此，我们概述了小脑深部核生理通路，通过离子通道和神经递质功能障碍负责癫痫发作的扩散。此外，我们还描述了细胞死亡后癫痫发作的变化，基因表达和蛋白质相互作用与各自的分子和解剖途径。 结论：最后，我们强调了小脑在癫痫发作向大脑传播中所起的作用，以及在某些耐药性癫痫亚型中如何抵消小脑的作用。

关键词: 小脑，神经解剖学，生理通路，癫痫传播，癫痫，基因，细胞凋亡。

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