摘要
背景与目的:严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)感染通常会导致神经系统表现。在本综述中,我们旨在探讨COVID-19早期诊断和神经表现预后的潜在神经影像学标志物。 方法:我们的研究在PROSPERO前瞻性系统评价注册(Prospective Register of Systematic Reviews,简称PROSPERO)中注册,协议为CDR42021265443。根据系统评价和荟萃分析(PRISMA)指南的首选报告项目,我们选择了51篇研究进行全稿分析。 结果:磁共振成像(MRI)是最常见的成像方法。神经损伤的模式、部位、体征和症状各不相同。这些表现可能是由直接的病毒感染引起的,也很可能是由凝血功能障碍、低氧血症和免疫反应等间接机制引起的。 结论:研究的异质性排除了任何研究结果的泛化。脑磁共振成像是最具信息量的影像学检查。缺少包括COVID-19全谱在内的人口研究。未来仍需要进行人群研究,评估所有COVID-19严重程度的急性和慢性神经系统表现。
关键词: 影像学,PET-CT, MRI, COVID-19, SARS-CoV-2,脑,神经学。
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