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当代肿瘤药物靶点

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ISSN (Print): 1568-0096
ISSN (Online): 1873-5576

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Review Article

非编码RNA对乳腺癌进展的调控

卷 20, 期 10, 2020

页: [757 - 767] 页: 11

弟呕挨: 10.2174/1568009620666200712144103

价格: $65

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摘要

背景：乳腺癌(BC)是全球女性癌症相关死亡的主要原因。我们对BC侵袭和转移的分子机制的了解仍然不够。最近的研究为非编码RNA (ncRNAs)的前瞻性贡献以及这些ncRNAs与乳腺癌发生的不同交互机制之间的关联提供了令人信服的证据。MicroRNAs (微小RNAs)和lncRNAs (长链非编码RNAs)作为一类非编码RNA在包括BC在内的多种恶性肿瘤的发病机制中得到了广泛的研究。 目的：在本综述中，我们的目的是更好地了解miRNAs和lncRNAs在BC发生发展中的作用，以及它们的潜在机制，这可能有助于监测生物标志物的开发和有效防治BC的治疗策略的制定。 结论：

关键词: 乳腺癌，微小RNA

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