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Current Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 0929-8673
ISSN (Online): 1875-533X

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Editorial

The Role of Endothelium in Cardiovascular Diseases: New Insights

Author(s): Gerasimos Siasos

Volume 27, Issue 7, 2020

Page: [1019 - 1020] Pages: 2

DOI: 10.2174/092986732707200316164051

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[1]
Siasos, G.; Tousoulis, D.; Siasou, Z.; Stefanadis, C.; Papavassiliou, A.G. Shear stress, protein kinases and atherosclerosis. Curr. Med. Chem., 2007, 14(14), 1567-1572.
[http://dx.doi.org/10.2174/092986707780831087] [PMID: 17584064]
[2]
Tousoulis, D.; Georgakis, M.K.; Oikonomou, E.; Papageorgiou, N.; Zaromitidou, M.; Latsios, G.; Papaioannou, S.; Siasos, G. Asymmetric dimethylarginine: clinical significance and novel therapeutic approaches. Curr. Med. Chem., 2015, 22(24), 2871-2901.
[http://dx.doi.org/10.2174/0929867322666150625095046] [PMID: 26112145]
[3]
Siasos, G.; Oikonomou, E.; Zaromitidou, M.; Kioufis, S.; Kokkou, E.; Mourouzis, K.; Vlasis, K.; Vavuranakis, M.; Stone, P.H.; Papavassiliou, A.G.; Tousoulis, D. Clopidogrel response variability is associated with endothelial dysfunction in coronary artery disease patients receiving dual antiplatelet therapy. Atherosclerosis, 2015, 242(1), 102-108.
[http://dx.doi.org/10.1016/j.atherosclerosis.2015.07.009] [PMID: 26188531]
[4]
Siasos, G.; Zografos, T.; Oikonomou, E.; Papavassiliou, A.G.; Stefanadis, C.; Tousoulis, D. Flow-mediated dilation: is it just a research tool or a useful biomarker for cardiovascular prognosis. Int. J. Cardiol., 2015, 180, 154-157.
[http://dx.doi.org/10.1016/j.ijcard.2014.11.209] [PMID: 25438239]
[5]
Zaric, B.; Obradovic, M.; Trpkovic, A.; Banach, M.; Mikhailidis, D.P.; Isenovic, E.R. Endothelial dysfunction in dyslipidaemia: molecular mechanisms and clinical implications. Curr. Med. Chem., 2020, 27(7), 1021-1040.
[http://dx.doi.org/10.2174/0929867326666190903112146] [PMID: 31480995]
[6]
Behrendt, A.; Wulfmeyer, V.; Hammann, E.; Muppa, S.K.; Pal, S. Profiles of second- to fourth-order moments of turbulent temperature fluctuations in the convective boundary layer: first measurements with rotational Raman lidar. Atmos. Chem. Phys., 2015, 15, 5485-5500.
[http://dx.doi.org/10.5194/acp-15-5485-2015]
[7]
Giannotti, G.; Landmesser, U. Endothelial dysfunction as an early sign of atherosclerosis. Herz, 2007, 32(7), 568-572.
[http://dx.doi.org/10.1007/s00059-007-3073-1] [PMID: 17972030]
[8]
Landmesser, U.; Engberding, N.; Bahlmann, F.H.; Schaefer, A.; Wiencke, A.; Heineke, A.; Spiekermann, S.; Hilfiker-Kleiner, D.; Templin, C.; Kotlarz, D.; Mueller, M.; Fuchs, M.; Hornig, B.; Haller, H.; Drexler, H. Statin-induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthase. Circulation, 2004, 110(14), 1933-1939.
[http://dx.doi.org/10.1161/01.CIR.0000143232.67642.7A] [PMID: 15466656]
[9]
Perticone, F.; Ceravolo, R.; Pujia, A.; Ventura, G.; Iacopino, S.; Scozzafava, A.; Ferraro, A.; Chello, M.; Mastroroberto, P.; Verdecchia, P.; Schillaci, G. Prognostic significance of endothelial dysfunction in hypertensive patients. Circulation, 2001, 104(2), 191-196.
[http://dx.doi.org/10.1161/01.CIR.104.2.191] [PMID: 11447085]
[10]
Spartalis, M.; Spartalis, E.; Athanasiou, A.; Paschou, S.A.; Kontogiannis, C.; Georgiopoulos, G.; Iliopoulos, D.C.; Voudris, V. The role of the endothelium in premature atherosclerosis: Molecular mechanisms. Curr. Med. Chem., 2020, 27(7), 1041-1051.
[http://dx.doi.org/10.2174/0929867326666190911141951] [PMID: 31544711]
[11]
Oikonomou, E.; Siasos, G.; Tsigkou, V.; Bletsa, E.; Panoilia, M.E.; Oikonomou, I.N.; Simanidis, I.; Spinou, M.; Papastavrou, A.; Kokosias, G.; Zaromitidou, M.; Stampouloglou, P.; Spartalis, M.; Vavuranakis, M.; Stefanadis, C.; Papavassiliou, A.G.; Tousoulis, D. Coronary artery disease and endothelial dysfunction: Novel diagnostic and therapeutic approaches. Curr. Med. Chem., 2020, 27(7), 1052-1080.
[http://dx.doi.org/10.1161/10.2174/0929867326666190830103219] [PMID: 31470773]
[12]
Spartalis, E.; Spartalis, M.; Athanasiou, A.; Paschou, S.A.; Patelis, N.; Voudris, V.; Iliopoulos, D.C. Endothelium in aortic aneurysm disease: New insights. Curr. Med. Chem., 2020, 27(7), 1081-1088.
[http://dx.doi.org/10.2174/0929867326666190923151959] [PMID: 31549591]
[13]
Tentolouris, A.; Eleftheriadou, I.; Tzeravini, E.; Tsilingiris, D.; Paschou, S.A.; Siasos, G.; Tentolouris, N. Endothelium as a therapeutic target in diabetes mellitus: from basic mechanisms to clinical practice. Curr. Med. Chem., 2019, 27(7), 1089-1131.
[http://dx.doi.org/10.2174/0929867326666190119154152] [PMID: 30663560]

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