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Review Article

广谱抗原虫药物的研究进展

卷 28, 期 3, 2021

发表于: 03 March, 2020

页: [583 - 606] 页: 24

弟呕挨: 10.2174/0929867327666200303170000

价格: $65

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摘要

由布鲁氏锥虫、克氏锥虫、利什曼原虫、溶组织内阿米巴、蓝氏贾第虫、疟原虫和阴道毛滴虫引起的感染是大量人类寄生虫病的一部分。它们每年导致超过5亿人感染。这些原生动物寄生虫既影响低收入国家，也影响高收入国家，它们的药物治疗有限。因此，在临床前开发的新的更有效的药物可以改善寄生虫感染的整体治疗，即使它们的作用机制尚不清楚。本文就近年来已报道的抗原虫药物(二胺、胍、喹啉、苯并咪唑、噻唑、重氮萘及其衍生物)作为寄生虫病药物治疗的新选择进行了综述。

关键词: 抗原生动物药，药物，布鲁氏锥虫，克氏锥虫，利什曼原虫，兰氏贾第虫，阴道毛滴虫，疟原虫，痢疾阿米巴

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